Assessment of human dietary exposure to arsenic through rice

Davis, Matthew; Signes-Pastor, Antonio J.; Argos, Maria; Slaughter, Francis; Pendergrast, Claire; Punshon, Tracy; Gossai, Anala; Ahsan, Habibul

doi:10.1016/j.scitotenv.2017.02.119

Cited by 109 publications

(50 citation statements)

References 63 publications

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“…Only a few studies have assessed the association between childhood rice products consumption and urinary arsenic species concentration, as recently reviewed (Davis et al, 2017). Consumption of rice has been related to an increase of urinary DMA and MMA in children at 6–11 years old from the U.S. belonging to the National Health and Nutrition Examination Survey (NHANES) (Davis et al, 2014; deCastro et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain

Signes-Pastor

Vioque

Navarrete-Muñoz

et al. 2017

Environmental Research

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Inorganic arsenic (i-As) has been related to wide-ranging health effects in children, leading to lifelong concerns. Proportionally, dietary i-As exposure dominates in regions with low arsenic drinking water. This study aims to investigate the relation between rice and seafood consumption and urinary arsenic species during childhood and to assess the proportion of urinary i-As metabolites. Urinary arsenic species concentration in 400 4-year-old children living in four geographical areas of Spain, in addition to repeated measures from 100 children at 7 years of age are included in this study. Rice and seafood products intake was collected from children’s parents using a validated food frequency questionnaire (FFQ). At 4 years of age, children’s urine i-As and monomethylarsonic acid (MMA) concentrations increased with rice product consumption (p-value = 0.010 and 0.018, respectively), and urinary arsenobetaine (AsB) with seafood consumption (p = 0.002). Four-year-old children had a higher consumption of both rice and seafood per body weight and a higher urinary %MMA (p-value = 0.001) and lower % dimethylarsinic acid (DMA) (p-value = 0.017). This study suggests increased dietary i-As exposure related to rice product consumption among children living in Spain, and the younger ones may be especially vulnerable to the health impacts of this exposure also considering that they might have a lower i-As methylation capacity than older children. In contrast, seafood consumption did not appear to influence the presence of potentially toxic arsenic species in this population of children.

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Section: Discussionmentioning

confidence: 99%

Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain

Signes-Pastor

Vioque

Navarrete-Muñoz

et al. 2017

Environmental Research

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“…Our focus is specifically on iAs, since human exposure to organic arsenic species from seafood is dealt with in another paper in this issue (Taylor et al, this issue). Moreover, a specific, more detailed focus on rice is found in Davis et al (this issue).…”

Section: Human Exposure To Dietary Inorganic Arsenicmentioning

confidence: 99%

Human exposure to dietary inorganic arsenic and other arsenic species: State of knowledge, gaps and uncertainties

Cubadda

Jackson

Cottingham

et al. 2017

Science of The Total Environment

206

113

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Inorganic arsenic (iAs) is ubiquitous in the environment as arsenite (AsIII) and arsenate (AsV) compounds and biotransformation of these toxic chemicals leads to the extraordinary variety of organoarsenic species found in nature. Despite classification as a human carcinogen based on data from populations exposed through contaminated drinking water, only recently has a need for regulatory limits on iAs in food been recognized. The delay was due to the difficulty in risk assessment of dietary iAs, which critically relies on speciation analysis providing occurrence data for iAs in food – and not simply for total arsenic. In the present review the state of knowledge regarding arsenic speciation in food and diet is evaluated with focus on iAs and human exposure assessment through different dietary approaches including duplicate diet studies, market basket surveys, and total diet studies. The analytical requirements for obtaining reliable data for iAs in food are discussed and iAs levels in foods and beverages are summarized, along with information on other (potentially) toxic co-occurring organoarsenic compounds. Quantitative exposure assessment of iAs in food is addressed, focusing on the need of capturing variability and extent of exposure and identifying what dietary items drive very high exposure for certain population groups. Finally, gaps and uncertainties are discussed, including effect of processing and cooking, and iAs bioavailability.

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“…Exposure to arsenic is believed to be increasing, due to increased consumption of rice-based diets that confer increased risk for exposure [14]. In a case-control sub-study, plasma levels of arsenic were evaluated in relation to both type 1 and type 2 diabetes.…”

Section: Etiologic Factorsmentioning

confidence: 99%

Type 2 Diabetes in Youth: New Lessons from the SEARCH Study

Jensen

Dabelea

2018

Curr Diab Rep

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This body of evidence illustrates that type 2 diabetes continues to increase in incidence, although this increase may be partially attributable to increased surveillance. Disease management is influenced by the transition from adolescent to adult care and psychosocial factors may also contribute. This evidence also describes a high prevalence of disease-associated complications and comorbidities. Risk factors for cardiovascular disease are also highly prevalent. The SEARCH for Diabetes in Youth study continues to inform our understanding of the descriptive epidemiology and natural history of type 2 diabetes in youth. As the cohort matures, new opportunities emerge for building on our understanding of how youth-onset type 2 diabetes impacts future health.

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Assessment of human dietary exposure to arsenic through rice

Cited by 109 publications

References 63 publications

Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain

Concentrations of urinary arsenic species in relation to rice and seafood consumption among children living in Spain

Human exposure to dietary inorganic arsenic and other arsenic species: State of knowledge, gaps and uncertainties

Type 2 Diabetes in Youth: New Lessons from the SEARCH Study

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