Assessment of heavy metal content of commonly consumed herbal medicines in Sindh, Pakistan

Soomro, Amjad Hussain; Jatoi, Wahid Bux; Maitlo, Amjad Ali; Memon, Almas F.; Bhayo, Muhammad Siddique

doi:10.1007/s11356-021-13019-0

Cited by 8 publications

(2 citation statements)

References 21 publications

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“…The results obtained from our study were also compared with the permissible limits set for medicinal plants by FAO/WHO and the American Herbal Products Association (AHPA). It was detected that the heavy metal concentrations determined in the study materials were mostly within the permissible limits [ 111 – 122 ].…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Trace Element and Heavy Metal Levels of Some Ethnobotanically Important Medicinal Plants Used as Remedies in Southern Turkey in Terms of Human Health Risk

Karahan

2022

Biol Trace Elem Res

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Heavy metal accumulation in medicinal plants has increased dramatically in recent years due to agricultural and industrial activities leading to pollution of natural sources. This study is focused on the concentration of trace elements and heavy metals in aboveground parts of 33 medicinal plants from the Eastern Mediterranean of Turkey. Results showed that the Al concentrations varied between 4.368 and 1104.627, the B level varied between 47.850 and 271.479, Ca values ranged between 1971.213 and 22,642.895, Cd concentrations ranged between 0.011 and 0.651, Cr contents varied between 1.371 and 41.692, Cu values varied between 13.278 and 42.586, Fe concentrations varied between 20.705 and 1276.783, K levels ranged between 652.143 and 14,440.946, Mg concentrations varied from 336.871 to 1869.486, Mn contents varied between 46.383 and 849.492, Na concentrations varied between 167.144 and 3401.252, Ni values varied between 0.065 and 9.968, Pb levels ranged between 1.311 and 16.238, and Zn concentrations ranged between 67.250 and 281.954 mg kg −1 , respectively. Furthermore, Recommended Dietary Allowance (RDA) values for trace elements and estimated daily intake (EDI), target hazard quotient (THQ), and hazard index (HI) for heavy metals were calculated. The concentrations of heavy metals in some studied plants distributed in industrial and mining regions were found as slightly higher than the acceptable limits determined by WHO. Consequently, in order to prevent this heavy metal accumulation, when collecting medicinal aromatic plants, rural areas, close to clean rivers, or mountainous areas should be preferred, away from highway, mining, and industrial areas.

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Section: Resultsmentioning

confidence: 99%

Evaluation of Trace Element and Heavy Metal Levels of Some Ethnobotanically Important Medicinal Plants Used as Remedies in Southern Turkey in Terms of Human Health Risk

Karahan

2022

Biol Trace Elem Res

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“…Heavy metals levels above maximum permissible limits have been detected in herbal drugs globally 25 . These metals are harmful and could be detrimental to the health of consumers 26 . Based on the severity of health effects associated with heavy metals and the fact that huge portions of herbal drugs in Ghana do not undergo safety checks before consumption, it is prudent to investigate the herbal drugs to safeguard human health and preserve lives.…”

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confidence: 99%

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2022

IJPSR

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This study looked at heavy metal levels in selected registered herbal drugs of Asian and unregistered Ghanaian herbal drugs sold in Kumasi. It examined the health risks of the metals. It provided authorities with data to ensure that herbal drugs are strictly monitored and their metal levels evaluated to safeguard patrons' health. Dry ashing method was used on 10g of each of the herbal drug samples. Ashes were digested at 95 ºC with 70% HNO 3 and 70% HClO 4 (2:5v/v), and then metals were analyzed using Atomic Absorption Spectrophotometer (AAS). The Asian drugs recorded 27.42E-01 mg/kg (Fe), 28.17E-0 4 mg/kg (Pb), 27.43E-0 4 mg/kg, 12.06E-06E-0 2 mg/kg (As) and 79.72E-0 2 mg/kg (Cu) whilst the Ghanaian drugs recorded mean levels of 15.43E-01 mg/kg (Fe), 24.99E-02 mg/kg (Pb), 16.04E-03 mg/kg, 47.70E-0 4 mg/kg (AS) and 12.37E-0 4 mg/kg. Metal levels in drugs were below WHO and Pharmacopeia (China) permitted levels. HI and HQ were below 1, indicating that risk linked to the metals were acceptable. INTRODUCTION:Globally, approximately 80% of the population depend on herbal remedies to treat and manage diseases such as diabetes, stroke, and hypertension, among others 1 . Herbal drugs play a vital role in the healthcare delivery schemes of numerous countries and are either selfprescribed or recommended by herbal practitioners QUICK RESPONSE CODE

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Heavy metals and trace elements detected in the leaves of medicinal plants collected in the southeast part of Turkey

et al. 2021

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Assessment of heavy metal content of commonly consumed herbal medicines in Sindh, Pakistan

Cited by 8 publications

References 21 publications

Evaluation of Trace Element and Heavy Metal Levels of Some Ethnobotanically Important Medicinal Plants Used as Remedies in Southern Turkey in Terms of Human Health Risk

Evaluation of Trace Element and Heavy Metal Levels of Some Ethnobotanically Important Medicinal Plants Used as Remedies in Southern Turkey in Terms of Human Health Risk

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Heavy metals and trace elements detected in the leaves of medicinal plants collected in the southeast part of Turkey

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