Assessment of health status and program performance in patients on long-term oxygen therapy

Hernández, Carme; Aibar, Jesús; Batlle, Jordi de; Gomez-Cabrero, David; Soler, Néstor; Durán-Tauleria, Enric; Garcia‐Aymerich, Judith; Altimiras, Xavier López; Gómez, Mònica; Agustí, Àlvar; Escarrabill, Joan; Font, David García; Roca, Josep

doi:10.1016/j.rmed.2015.01.005

Cited by 18 publications

(14 citation statements)

References 32 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, data on reevaluation were reported only for a minority of patients. Similarly, rates of reevaluation have been reported to be low at one center in Spain 10 and higher in Denmark. 12 Currently, 75% of patients fulfill the criteria of a PaO 2 .8.0 kPa on oxygen.…”

Section: Identified Areas For Improvementmentioning

confidence: 94%

“…10 Patients were frail and often had insufficient adherence to the therapy. Management, including that of smoking during oxygen therapy, also differs substantially between countries and settings.…”

mentioning

confidence: 99%

“…[1][2][3] A structured approach for valid prescription and management of LTOT is needed. 10 The prevalence of LTOT is relatively high, 20,21 and the incidence is projected to rise in the coming decades, especially among women. 20 LTOT is associated with considerable logistics and costs.…”

mentioning

confidence: 99%

See 2 more Smart Citations

A Nationwide Structure for Valid Long-Term Oxygen Therapy: 29 year prospective data in Sweden

Ahmadi

Larsson

Nilsson³

et al. 2017

Clinical Problems Others

View full text Add to dashboard Cite

Section: Identified Areas For Improvementmentioning

confidence: 94%

mentioning

confidence: 99%

See 1 more Smart Citation

A Nationwide Structure for Valid Long-Term Oxygen Therapy: 29 year prospective data in Sweden

Ahmadi

Larsson

Nilsson³

et al. 2017

Clinical Problems Others

View full text Add to dashboard Cite

“…2), on January 2017, two implementation studies were initiated at Barcelona-Esquerra: (i) Community-based management of CCP (intervention group, n = 3000) and (ii) Integrated care for patients under LTOT (intervention group, n = 500). 27 A codesign process (Supplementary Methods) following a Plan–Do–Study–Act methodology 28 will be carried out in each site by a multidisciplinary team including primary care professionals (general practitioners, nurses, and social workers), specialists (doctors and allied health professionals), technologists, patients, and caregivers.…”

Section: Methodsmentioning

confidence: 99%

Protocol for regional implementation of community-based collaborative management of complex chronic patients

Cano

Dueñas-Espín

Hernández

et al. 2017

npj Prim Care Resp Med

Self Cite

View full text Add to dashboard Cite

“…Co-morbidities in COPD have well-known negative impact on patients’ prognosis and a close association with high use of healthcare resources [16, 17]. Consequently, the question is: Is COPD a risk factor for co-morbidities?…”

Section: Introductionmentioning

confidence: 99%

From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration

et al. 2016

Self Cite

View full text Add to dashboard Cite

BackgroundDeep mining of healthcare data has provided maps of comorbidity relationships between diseases. In parallel, integrative multi-omics investigations have generated high-resolution molecular maps of putative relevance for understanding disease initiation and progression. Yet, it is unclear how to advance an observation of comorbidity relations (one disease to others) to a molecular understanding of the driver processes and associated biomarkers.ResultsSince Chronic Obstructive Pulmonary disease (COPD) has emerged as a central hub in temporal comorbidity networks, we developed a systematic integrative data-driven framework to identify shared disease-associated genes and pathways, as a proxy for the underlying generative mechanisms inducing comorbidity. We integrated records from approximately 13 M patients from the Medicare database with disease-gene maps that we derived from several resources including a semantic-derived knowledge-base. Using rank-based statistics we not only recovered known comorbidities but also discovered a novel association between COPD and digestive diseases. Furthermore, our analysis provides the first set of COPD co-morbidity candidate biomarkers, including IL15, TNF and JUP, and characterizes their association to aging and life-style conditions, such as smoking and physical activity.ConclusionsThe developed framework provides novel insights in COPD and especially COPD co-morbidity associated mechanisms. The methodology could be used to discover and decipher the molecular underpinning of other comorbidity relationships and furthermore, allow the identification of candidate co-morbidity biomarkers.Electronic supplementary materialThe online version of this article (doi:10.1186/s12859-016-1291-3) contains supplementary material, which is available to authorized users.

show abstract

Assessment of health status and program performance in patients on long-term oxygen therapy

Cited by 18 publications

References 32 publications

A Nationwide Structure for Valid Long-Term Oxygen Therapy: 29 year prospective data in Sweden

A Nationwide Structure for Valid Long-Term Oxygen Therapy: 29 year prospective data in Sweden

Protocol for regional implementation of community-based collaborative management of complex chronic patients

From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration

Contact Info

Product

Resources

About