Assessment of Health-Related Quality of Life and Risk Factors Associated With Pancreatitis in a Tertiary Care Hospital

Abstract

Objective: The objective of the study was to measure the health-related quality of life (HRQoL) in pancreatitis and to appraise the risk factors associated with the pancreatitis.
 Methods: A prospective observational study was performed with admitted cases of pancreatitis over 6 month’s period. A total of 150 patients were selected for the study. All data concerning risk factors were recorded and Short-Form-36 (SF-36) questionnaire was applied and quality of life (QOL) was analyzed in all patients with in study group.
 Results: All domains of (HRQoL) were assessed; it shows highest effect on role limitations due to physical health (36%), role limitations due to emotional problems (29%), role limitations due to physical health, and role limitations due to emotional problems (10%). Finally, our study revealed that there is a profound deterioration in physical components of QOL. The risk factors that majorly influence the QOL in association with disease were found to be alcohol consumption and smoking (70%).
 Conclusion: Pancreatitis remarkably diminishes the patient’s HRQoL which predominantly shows negative impact on physical health.

Quality of Life and Pain in Patients With Chronic Pancreatitis

“…20 The incidence of alcoholic CP is higher in men, which is believed to be due to the differences in lifestyle between men and women. 12,20,[50][51][52] The present study did not find a relationship between sex and QoL in the analyzed domains of the SF-36 questionnaire. This is consistent with the findings from a number of other studies.…”

“…This finding is consistent with other studies where pain was found to be the only clinical variable having a negative impact on all the domains investigated in the SF-36 questionnaire. [4][5][6][7][8][10][11][12][13][14]33,34 Both the present study and other studies have shown that the intensity of pain is of key significance and that it is positively correlated with the degree of impairment of QoL. 6,11,33,34 The intensity of pain is of greater significance than its frequency.…”

“…Quality of life impairment is a common finding in all studies on the QoL of CP patients, regardless of the type of assessment tool used. [4][5][6][8][9][10][11][12][13]31,32 However, it is a moot point as to which domain of QoL is most affected by the disease. In their multicenter study, Fitzsimmons et al 5 used a directed interview, which focused on changes in lifestyle necessitated by CP and addressed the issue of the use of alcohol.…”

“…The tools most commonly used to assess QoL in patients with pancreatic diseases are the World Health Organization Quality of Life-BREF (WHOQOL-BREF), the 36-Item Short Form Health Survey (SF-36), and its shortened version (SF-12) as well as other questionnaires with questions specific to pancreatic diseases, including the EORTC QLQ-C30 and EORTC QLQ-PAN26 questionnaires and the PANQOLI questionnaire, which includes a unique "self-worth" subscale. 4,[5][6][7][8][9][10][11][12][13] From a practical point of view, the SF-12 questionnaire, which is an abbreviated form of the SF-36 questionnaire used in this study, is the most reliable and the easiest to use in clinical practice. 4 The SF-36 is a generic psychometric tool and, as such, is not specific to CP.…”

“…The studies about QoL in chronic pancreatitis (CP) use different tools and tackle different themes, so it seems important to provide new insights and summarize published results. The tools most commonly used to assess QoL in patients with pancreatic diseases are the World Health Organization Quality of Life-BREF (WHOQOL-BREF), the 36-Item Short Form Health Survey (SF-36), and its shortened version (SF-12) as well as other questionnaires with questions specific to pancreatic diseases, including the EORTC QLQ-C30 and EORTC QLQ-PAN26 questionnaires and the PANQOLI questionnaire, which includes a unique “self-worth” subscale 4,5–13 …”