Assessment of Health-Related Quality of Life using the EQ-5D-3L in Individuals with Type 2 Diabetes Mellitus

Objective:To assess the health-related quality of life of Type 2 Diabetes mellitus patients attending outpatient departments of a tertiary hospital using EQ-5D-5L.Methods:The study was conducted at a tertiary care hospital in India. The quality of life of patients with type 2 Diabetes mellitus, age 18 years and older, attending outpatient departments of Medicine and Endocrinology was assessed with the help of EQ-5D-5L, a measure of self-reported health related quality of life. Data was analyzed to obtain EQ-5D-5L scores for the five dimensions and EQ VAS score. Correlation of EQ VAS score with different variables was analyzed.Results:Out of total 358 participants, 208 had comorbidities, hypertension being the most common. Mean age was 60.71 ± 11.41 years and 216 (58.9%) were female participants. Out of five dimensions, Mobility, Self-care, Usual activities, and Pain/discomfort were most affected in age group 71 years and above while anxiety/depression affected age group 18–30 years the most. Mean EQ VAS score was 78.83 ± 15.02. Female participants had significantly higher EQ VAS score (P = 0.00) than male participants. EQ VAS score showed significant negative correlation with uncontrolled state of diabetes (P = 0.000). There was significant difference in EQ VAS score between patients with and without comorbidities. (P =0.004) Cronbach alpha for EQ-5D-5L was 0.76.Conclusion:The results suggest that EQ-5D-5L is a reliable measure for assessing health related quality of life of patients with Type 2 Diabetes mellitus. Type 2 Diabetes adversely affects the quality of life of patients. Uncontrolled disease and comorbidities can further compromise the quality of life.

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“…[26] Pain/discomfort was the most common among the five Euroqol 5-D domains in several other studies also. [272829]…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in India using Eq 5D 5L

Parik

Patel

2019

Indian J Endocr Metab

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“…The reward function 𝑅(𝑎, 𝑠 ′ ) of our proposed model is shown in Equation ( 4), wh ′ The decrement values are referenced from other studies [31][32][33][34].…”

Section: Reward Rmentioning

confidence: 99%

Precision Medicine for Hypertension Patients with Type 2 Diabetes via Reinforcement Learning

Lee

Park

2022

JPM

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Precision medicine is a new approach to understanding health and disease based on patient-specific data such as medical diagnoses; clinical phenotype; biologic investigations such as laboratory studies and imaging; and environmental, demographic, and lifestyle factors. The importance of machine learning techniques in healthcare has expanded quickly in the last decade owing to the rising availability of vast multi-modality data and developed computational models and algorithms. Reinforcement learning is an appealing method for developing efficient policies in various healthcare areas where the decision-making process is typically defined by a long period or a sequential process. In our research, we leverage the power of reinforcement learning and electronic health records of South Koreans to dynamically recommend treatment prescriptions, which are personalized based on patient information of hypertension. Our proposed reinforcement learning-based treatment recommendation system decides whether to use mono, dual, or triple therapy according to the state of the hypertension patients. We evaluated the performance of our personalized treatment recommendation model by lowering the occurrence of hypertension-related complications and blood pressure levels of patients who followed our model’s recommendation. With our findings, we believe that our proposed hypertension treatment recommendation model could assist doctors in prescribing appropriate antihypertensive medications.

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“…Penelitian ini bertujuan untuk menerapkan asuhan kefarmasian dan mengetahui pengaruhnya terhadap outcome klinis dan kualitas hidup pasien DM tipe 2 di Apotek. (10). Kuesioner ini memiliki 5 dimensi yaitu, 1) mobilitas/berjalan, 2) perawatan diri, 3) kegiatan yang biasa dilakukan, 4) rasa kesakitan/tidak nyaman, 5) rasa cemas/depresi dengan masing-masing dimensi memiliki 3 level pertanyaan yaitu 1) tidak masalah, 2) bermasalah sedang dan 3) bermasalah berat.…”

Section: Pendahuluanunclassified

Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2

Khairunnisa

Rawitri

Wiryanto

et al. 2021

JFI

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Peran apoteker dalam asuhan kefarmasian telah terbukti meningkatkan outcome terapi pada pasien diabetes melitus (DM) di berbagai negara. Penelitian ini bertujuan untuk menerapkan asuhan kefarmasian dan mengetahui pengaruhnya terhadap outcome klinis dan kualitas hidup pasien DM tipe 2 di Apotek. Penelitian ini menggunakan metode eksperimental komparatif dengan desain penelitian kohort-studi prospektif sebelum dan setelah intervensi terhadap 38 pasien DM tipe 2 yang memenuhi kriteria inklusi di salah satu Apotek di Kota Medan pada bulan Agustus-Desember 2020. Data outcome klinis meliputi kadar gula darah (KGD) sewaktu dan nilai HbA1c diperoleh dari pemeriksaan langsung pada pasien, dan data kualitas hidup diperoleh menggunakan kuesioner EQ-5D-3L. Data dianalisis menggunakan uji Wilcoxon Signed Rank dan uji Friedman dalam program SPSS V22.0. Hasil penelitian menunjukkan nilai KGD sewaktu rata-rata sebelum intervensi sebesar 278,58 ± 75,27 mg/dl dan setelah intervensi terjadi penurunan menjadi 179,68 ± 14,01 mg/dl (α<0,05), nilai HbA1c 9,021 ± 1,029% menjadi 8,368 ± 1,049% (α<0,05). Terjadi peningkatan secara signifikan indeks kualitas hidup rata-rata sebelum intervensi sebesar 0,849 ± 0,126 dan setelah intervensi menjadi 0,967 ± 0,065 (α<0,05). Berdasarkan hasil penelitian disimpulkan bahwa penerapan asuhan kefarmasian berpengaruh terhadap peningkatan outcome klinis dan kualitas hidup pada pasien DM tipe 2 di Apotek.

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Assessment of Health-Related Quality of Life using the EQ-5D-3L in Individuals with Type 2 Diabetes Mellitus

Cited by 6 publications

References 24 publications

Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in India using Eq 5D 5L

Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in India using Eq 5D 5L

Precision Medicine for Hypertension Patients with Type 2 Diabetes via Reinforcement Learning

Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2

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