Assessment of free microvascular flap perfusion by intraoperative fluorescence angiography in craniomaxillofacial surgery

Preidl, Raimund; Schlittenbauer, Tilo; Weber, Manuel; Neukam, Friedrich Wilhelm; Wehrhan, Falk

doi:10.1016/j.jcms.2015.03.013

Cited by 18 publications

(22 citation statements)

References 17 publications

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“…Followed by the above mentioned changes in blood flow regulation, a reactive increase in blood flow of the macrocirculation system can be observed, while blood flow in the microcirculation system decreases . Arteriovenous shunts, so‐called “choke vessels,” seem to have a significant influence on these opposing changes.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the hemodynamics of both macro‐ and microcirculatory vessels cannot be compared with healthy tissue. Micro‐ and macrocirculation change severely after flap raising and restoring of the perfusion following flap transfer, which is mainly ascribed to postischemic metabolic changes and denervation (sympathectomy) of the flap tissue . If, and to what extend active postoperative tissue warming has an influence on free flap microcirculation remains unknown and is the object of this study.…”

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confidence: 99%

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Impact of active thermoregulation on the microcirculation of free flaps

et al. 2015

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Impact of active thermoregulation on the microcirculation of free flaps

et al. 2015

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“…Ample evidences also suggest that ASL has good agreement with other measures of cerebral perfusion assessment 29–31. Some reports mentioned that intraoperative indocyanine green (ICG) video angiography combined with haemodynamic parameter analysis obtained by Flow 800 software is useful for intraoperative monitoring of regional CBF in cerebrovascular disease 32–34. It can provide detailed images for vascular architecture, flow direction and blood flow transit, which provides real-time cerebral flow velocity and superficial perfusion of local brain 35.…”

Section: Introductionmentioning

confidence: 99%

Multimodal neuronavigation-guided precision bypass in adult ischaemic patients with moyamoya disease: study protocol for a randomised controlled trial

Zhao

et al. 2019

BMJ Open

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IntroductionRevascularisation surgery is an important treatment of moyamoya disease (MMD). Several general methods of revascularisation had been used: direct, indirect and combined techniques. However, there had been no reports about the criteria of recipient arteries selection in bypass surgery for MMD. Surgeons usually choose the recipient arteries by their own experiences. Their choices of the recipient arteries are various and may contribute the different outcome of patients. The purpose is to identify utility and efficacy of precision bypass guided by multimodal neuronavigation of MMD in a prospective randomised controlled trial.Method and analysisThis study is a prospective randomised controlled clinical trial. This study will enrol a total of 100 eligible patients. These eligible patients will be randomised to the empirical bypass group and the multimodal neuronavigation-guided precision bypass group in a 1:1 ratio. Patient baseline characteristics and MMD characteristics will be described. In the multimodal neuronavigation-guided group, the blood velocity and blood flow of the recipient arteries will be identified. Surgical complications and outcomes at pretreatment, post-treatment, at discharge and at 3 month, 6 month, 12 month and end of trial will be analysed with CT perfusion, MRI, digital subtraction angiography, modified Rankin Scale, National Institute of Health Stroke Scale and modified Barthel Scale. This trial will determine whether multimodal neuronavigation-guided precision bypass is superior to empirical bypass in patients with MMD and identify the safety and efficacy of multimodal neuronavigation-guided precision bypass.Ethics and disseminationThe study protocol and written informed consent were reviewed and approved by the Clinical Research Ethics Committee of Peking University International Hospital. Study findings will be disseminated in the printed media. The study started in August, 2018 and expected to be completed in December, 2020.Trial registration numberNCT03516851; Pre-results.

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“…In today's therapy of head and neck defects, surgical reconstruction with the aid of pedicle or microvascular free flaps is a standard procedure (Preidl et al 2015) (Wong and Wei 2010). In specialized centers these are already routine techniques (Zhang et al 2015;Neligan 2013).…”

Section: Introductionmentioning

confidence: 99%