Assessment of Environmental Exposure to Benzene: Traditional and New Biomarkers of Internal Dose

Lovreglio, Maria Nicolà D’Errico Piero; Fustinoni, Silvia; Drago, Ignazio; Barbieri, Anna; Carrieri, Mariella; Apostoli, Pietro; Soleo, Leonardo

doi:10.5772/16915

Cited by 3 publications

(3 citation statements)

References 57 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Las estaciones de servicio de gasolina (es) despiden compuestos orgánicos volátiles (cov) durante el trasvase de la bomba de despacho al auto. Estos vapores de gasolina constituyen importantes fuentes puntuales de emisión al aire de compuestos, como el benceno, tolueno, etilbenceno y xileno (btex) en las zonas [7,11]. No obstante, desde el punto de vista toxicológico, es el benceno el contaminante más importante de los btex, ya que varios estudios han demostrado que afecta a los sistemas nervioso, linfático, hematopoyético, hepático, renal, además de ser considerado como cancerígeno para el hombre [12,20].…”

Section: Introductionunclassified

Aglomeración urbana en la estimación de escenarios de riesgo sanitario por emisiones de gasolineras: el caso de Ensenada, Baja California

Zarate

García

Villada-Canela

et al. 2017

Rev. Fac. Nac. Salud Pública

View full text Add to dashboard Cite

show abstract

Section: Introductionunclassified

Aglomeración urbana en la estimación de escenarios de riesgo sanitario por emisiones de gasolineras: el caso de Ensenada, Baja California

Zarate

García

Villada-Canela

et al. 2017

Rev. Fac. Nac. Salud Pública

View full text Add to dashboard Cite

show abstract

“…VOCs can have adverse effects on the human health and environment. Benzene, toluene, xylene isomers, phenol, and methyl ethyl ketone (MEK) are the most consumed VOCs and they are used in various industries (5)(6)(7). Benzene is a known human group 1 carcinogen [International Agency for Research on Cancer (IARC)] and skin A1 carcinogen [American Conference of Governmental Industrial Hygienists (ACGIH)], and causes hematotoxicity, aplastic anemia, acute myelogenous leukemia, and lymphoma (8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Biological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in Southern Iran

Rahimpoor

Bahrami

Assari

et al. 2014

JOHE

View full text Add to dashboard Cite

Received: July 2015, Accepted: August 2015 Background: Volatile organic compounds (VOCs), including carcinogens and toxic compounds, are produced in petrochemical industries. We undertook this study in order to study workers' respiratory exposure to different VOC concentrations and compare the results with the urinary levels of its metabolites and study the correlation between them in petrochemical industries. Materials and Methods: Exposure to benzene, toluene, xylene isomers, phenol, and methyl ethyl ketone (MEK) was evaluated in 104 male subjects using personal sampling pump and charcoal sorbent tube at the breathing zone and analyzed using gas chromatography-mass spectrometry (GC-MS). The urine samples were analyzed using high-performance liquid chromatography (HPLC-UV) and gas chromatography-flame ionization detector (GC-FID). Results:The mean concentration of urinary trans,trans-muconic acid (t,t-MA), was 1431 µg/g creatinine and hippuric acid, methyl hippuric acid, phenol, and MEK were, 0.394, 0.444, 0.098 g/g creatinine, and 0.15 mg/l. The mean concentration of benzene in the breathing zone was greater than the threshold limit value (TLV) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). Conclusions:In this study, a more significant relationship was found between benzene in breathing zone and urinary t,t-MA in those exposed to benzene in concentrations higher than 1 ppm (r 2 = 0.89) than lower than 1 ppm. Moreover, the same results were observed for other hydrocarbons and their level of urinary biological index. A more significant relationship was observed between phenol in breathing zone and urine through exposure to airborne phenol in concentrations of higher than 0.049 ppm than lower than 0.049 ppm (r 2 = 0.75). The relationship between MEK in breathing zone and urinary MEK was more significant in concentrations of higher than 0.1 ppm (r 2 = 0.79) than lower than 0.1 ppm.

show abstract

“…Benzene is one of the most important components of the BTEX group, from the toxicological point of view, since it is considered carcinogen for humans. The presence of benzene from GS is due to the emissions that happen during distribution, loading and unloading and transportation of gasoline [3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Intra-Urban Mobility in the Estimation of Risk Scenarios by BTEX Emissions

Villada-Canela

et al. 2016

Preprint

View full text Add to dashboard Cite

The population's mobility in urban areas is a necessary variable in the modeling of risk scenarios caused by atmospheric contamination. The inclusion of this concept makes static models more dynamic while considering people within a city to be an entity with complex mobility processes. We propose a conceptual and methodological tool to make the representation of the social, economic and territorial components, as well as the patterns in the population´s mobility to delimitate risk areas for human health by exposure of contaminants. In the volatile organic compounds (VOC), benzene, ethylbenzene, toluene and xylene (BTEX) are amongst the most dominant substances in fugitive vapor emissions in gas stations (GS). In urban areas, the exposure to BTEX by residential proximity and proximity to other facilities, which cause intra-urban agglomeration, can impact and affect human health. This model seeks to facilitate the focalization, identification and prioritization of risk areas by BTEX environmental contamination. This article goes beyond de conceptual framework. It suggests methodological and instrumental aspects to be applied in other cities. The government agencies must consider these results when establishing rules, permissions and procedures to reduce environmental pollution for managing the risk in a complex urban environment.

show abstract

Assessment of Environmental Exposure to Benzene: Traditional and New Biomarkers of Internal Dose

Cited by 3 publications

References 57 publications

Aglomeración urbana en la estimación de escenarios de riesgo sanitario por emisiones de gasolineras: el caso de Ensenada, Baja California

Aglomeración urbana en la estimación de escenarios de riesgo sanitario por emisiones de gasolineras: el caso de Ensenada, Baja California

Biological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in Southern Iran

Intra-Urban Mobility in the Estimation of Risk Scenarios by BTEX Emissions

Contact Info

Product

Resources

About