Since 2008, the Eagle Ford Shale has been one of the most active U.S. oil and gas plays. Regional variations of the frequency (cyclicity) and thickness of organic-rich marl and limestone interbeds influence well completion design, and these variations may be related to well production performance. To better understand the impacts of lithologic cyclicity and reservoir and fluid properties on well performance, we conducted an integrated, regional study using well logs, production data, and PVT reports.Regionally, the Eagle Ford Shale is composed of 3 units. The Lower Eagle Ford consists of cyclic, interbedded organic-rich marl and limestone. To analyze lithologic cyclicity of the Lower Eagle Ford Shale in South Texas, We evaluated gamma ray logs from more than 500 vertical wells. A Matlab script was developed to count the numbers of organic-rich marl and limestone interbeds. Average bed thickness was calculated at each well and was mapped regionally. The numbers of both limestone and organic-rich marl interbeds increase from less than 2 in the northwest to more than 20 on the southeast. Lithologic cyclicity is greatest in La Salle and Karnes Counties, which are the most productive gas and oil regions, respectively.Eagle Ford Shale reservoir and fluid properties from PVT reports were mapped to further evaluate regional variations of fluid types and well performance. Reservoir pressure, pressure gradient, oil gravity, and gas specific gravity were mapped. Reservoir pressure and pressure gradient are greatest on the northeast. Oil gravity and gas specific gravity maps suggest increasing thermal maturity from northwest to southeast, with increasing depth.Well production rates are strongly influenced by lithologic cyclicity, pressure, and fluid properties. Understanding these relations in the lower Eagle Ford Shale should assist with optimizing completion design and stimulation strategies. The results of this study provide a better understanding of Eagle Ford Shale reservoir characteristic and well performance, and the study approach may be used to assess productivity of other shale plays.