Assessment of drug use pattern using World Health Organization core drug use indicators at Secondary Care Referral Hospital of South India

Prasad, Priya; Rudra, J Thippe; Vasanthi, P; Sushitha, U; Sadiq, Mohammad Jaffar; Narayana, G

doi:10.4103/2348-3334.158683

Cited by 29 publications

(47 citation statements)

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“…[27][28][29][30][31] Regional variations within the country has been demonstrated in prescriptions from various parts of India, with value varying between 2.7 and 3.2. [31][32][33][34][35][36][37][38] While the present study findings of 2.5 drugs per prescription are slightly lower than from other parts of India, it is still higher than the recommended international standards.…”

Section: Discussionmentioning

confidence: 54%

Practices regarding prescription and dispensing of drugs in a tertiary care hospital in rural West Bengal, India

Bandyopadhyay

Dhar

Mukherjee

et al. 2017

Int J Basic Clin Pharmacol

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Background: Irrational prescription practices are a distressing global problem, especially in the developing countries. A study was conducted to assess the patterns of prescribing and dispensing drugs in a tertiary healthcare centre serving a large rural population in the eastern India.Methods: A cross-sectional observational study was conducted from July-September 2016 in the general out-patient department and the institution pharmacy of a tertiary care hospital of West Bengal, India. Data were congregated by collection and review of individual prescriptions, measuring the time of interaction between patients and prescribers/dispensers, and conducting patient interviews at exit.Results: Analysis of the collected and tabulated data revealed that after average, 2.5 medicines were prescribed per prescription, with 95.26% being under their generic name. Of the drugs prescribed, 95.79% were from the essential drug list. The average consultation time was 150.0s (SD 62.3s) and average dispensing time was 81.5s (SD 51.2s). Of the drugs prescribed, 86.12% of drugs were actually dispensed from the institution pharmacy but none of the drugs were labeled. The percentage of prescriptions with an antibiotic was 47.83%, while injections were recorded on in 2.83% of the prescriptions. Percentage of patients who had knowledge of the dosage of the drugs prescribed to them was 91.67%.Conclusions: While the study found high percentages of drugs prescribed under generic names high percentage of drugs actually prescribed from the Institution Pharmacy, prescription of drugs from the Essential Drugs List, and a low number of injections per prescription conforming to WHO set standards, it also found a lack of drug labelling, high percentage of prescription of antibiotics to be indicators that do not conform with the WHO set international standards.

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Section: Discussionmentioning

confidence: 54%

Practices regarding prescription and dispensing of drugs in a tertiary care hospital in rural West Bengal, India

Bandyopadhyay

Dhar

Mukherjee

et al. 2017

Int J Basic Clin Pharmacol

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“…7,8 In another study from South India, the percentage of injections was as low as 1.6%. 9 It is a well-accepted fact that parenteral therapy is significantly costlier, because of the higher price for the formulations, the cost of the syringes as well as nursing charges. The significant reduction in the use of injectables in this institution deserves appreciation.…”

Section: Discussionmentioning

confidence: 99%

“…Surveys from different parts of the country reveal highly divergent figures-Nagpur (Central India) 49%, South India 43%, Bhopal (3.6%). [8][9][10] On the other hand, an Ethiopian study shows that 99% prescriptions were in generic names. 11 No wonder the Medical Council of India, the regulatory authority for practice of modern medicine, has recently come out with a stipulation that every physician should prescribe drugs with generic names legibly and preferably in capital letters.…”

Section: Discussionmentioning

confidence: 99%

A prospective study on the pattern of antibiotic use in a tertiary care hospital

Mani

Hariharan

2017

Int J Basic Clin Pharmacol

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Background: Indiscriminate use of antimicrobials is rampant throughout India, and this is a matter of serious concern. There are several reports linking antibiotic usage to bacterial resistance. Towards addressing this problem, community wise surveillance needs to be undertaken to monitor antibiotic exposure including their misuse. This study was meant to assess the extent and pattern of antibiotic use in a tertiary care facility. Methods: Subjects for study were patients attending a suburban hospital in central Kerala. Case records of patients who were prescribed systemic antibiotics were perused for relevant data. Seriously ill patients were excluded from the study. Results: 610 encounters with antibiotics could be identified from a total of around 2000 patient records, indicating an encounter rate of 29%; which is quite acceptable as per the WHO standard of prescribing indicators. However, more than 70% of prescriptions carried only brand names of medications. Use of antibiotics was mostly on the basis of clinical symptoms (presumptive), and culture reports were not given due credence. Prescriptions were invariably therapeutic in nature, and the concepts of surgical prophylaxis conveniently given a go by. The most common infections were those of the Upper Respiratory Tract (URTI), followed by skin and soft tissue infections. Ampicillin, azithromycin and cefuroxime were the most frequently prescribed agents. More than one third of infections were treated with a combination of antimicrobials. A general temptation for using cephalosporin -betalactamase inhibitor combinations could be related to the aggressive promotional policies of the pharmaceutical industry. Conclusions: The overall antibiotic encounter rate is acceptable as per WHO standards. But the tendency for using injections as well as antibiotic combinations is very high. Prophylactic use of antibiotics in surgical procedures is not being followed at all. A serious attempt needs to be made to implement National Guidelines for use of antimicrobials.

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“…24 In our study, percentage of drugs prescribed by generic names and percentage of drugs from NLEM is much more compared to similar studies done by Anuj et al and Prasad et al which indicates a good trend of prescribing. 25,26 Even Medical Council of India now mandates all physicians to write the prescriptions in terms of generic names. A higher percentage of drugs from NLEM are more economical so that the drugs become affordable to even the poor patients as essential drugs are cheaper compared to those which are not in the list.…”

Section: 13mentioning

confidence: 99%

WHO core prescribing indicators in patients with allergic contact dermatitis in a coastal town of South India

Divyashanthi

Kolasani

Jayabal

et al. 2017

Int J Basic Clin Pharmacol

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Assessment of drug use pattern using World Health Organization core drug use indicators at Secondary Care Referral Hospital of South India

Cited by 29 publications

References 0 publications

Practices regarding prescription and dispensing of drugs in a tertiary care hospital in rural West Bengal, India

Practices regarding prescription and dispensing of drugs in a tertiary care hospital in rural West Bengal, India

A prospective study on the pattern of antibiotic use in a tertiary care hospital

WHO core prescribing indicators in patients with allergic contact dermatitis in a coastal town of South India

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