Assessment of Dose Calibrators Performance in Nuclear Medicine Department in Sudan

Alameen, Suhaib; bdelfatah, Ahamed M.; Almubarak, Mubarak

doi:10.21276/sajp.2016.5.6.4

Cited by 2 publications

(3 citation statements)

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“…The results of quality control tests revealed that the parameters monitored for dose calibrators were within the limits of international standards. (±5%) [12].…”

Section: Discussionmentioning

confidence: 99%

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Comparative Assesment of Dose Calibrators Used in Nuclear Medicine

KARACA¹

2020

MEJS

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Dose calibrators are used to measure the amount of radioactive to be given to the patient. It is necessary to determine the correct dose and measure the amount of radioactive material with the least possible error. To minimize these potential errors, quality control (QC) tests should be carried out periodically according to the United States Nuclear Regulatory Authority (NRC). ATOM LAB 400 (serial number:11070208 ) and 500 (serial number: 15091215) dose calibrators that are actively used in our clinic were used. The aim of this study is to compare with another recently calibrated dose calibrator to verify the dose calibrator that needs to be updated is working properly. QC tests were performed on both dose calibrators. Test results of the currently certified dose calibrator and ATOM LAB 400 dose calibrator whose certificate will be updated were found to be compatible with each other. The tests performed on both dose calibrators remained with the error limits. The calibration certificate of the ATOM LAB 400 calibrator has been updated in accordance with NRC protocol.

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“…The results of quality control tests revealed that the parameters monitored for dose calibrators were within the limits of international standards. (±5%) [12].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, each activity planned to be given to patients must be measured in a dose calibrator. This activity should be known for the need for radiation protection and successful treatments or good quality imaging [1,2].…”

Section: Introductionmentioning

confidence: 99%

Comparative Assesment of Dose Calibrators Used in Nuclear Medicine

KARACA¹

2020

MEJS

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“…This protein acts as a negative regulator of cell growth and controls regulatory proteins of the cell cycle of "cyclin D1" and Rb functioning and expression levels. These proteins are involved in the progression of the cell cycle from the G1-phase to the S-phase in prostate cancer cells [63,64] .…”

Section: Mechanism Of Actionmentioning

confidence: 99%

Comprehensive Review on Mechanistic Insights, Optimal Dosages, and Safety Prospective of Natural Products in Anticancer Therapeutics

Chaudhry,

Zeenia,

Akim

et al. 2024

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Cancer remains a formidable global health challenge, necessitating sustained research efforts to develop innovative and efficacious therapeutic modalities. The exploration of alternative cancer therapies has gained prominence, given the adverse side effects associated with conventional treatments like chemotherapy. Natural medicines, particularly those derived from botanical sources, emerge as a potentially more viable option for cancer treatment within the confines of therapeutic and safe dosage parameters. This comprehensive review elucidates the effective mechanisms and safety profiles related to the dosage of these natural compounds. The literature under consideration spans and has been meticulously curated from reputable databases, including PubMed, Scopus, and Google Scholar. Noteworthy natural substances encompassed in this scrutiny include gossypol, curcumin, resveratrol, genistein, anthocyanin, and hispidulin. The review outlines their respective mechanisms, therapeutic dosages, and safety perspectives within the context of cancer treatment. These compounds manifest diverse anticancer effects, ranging from the induction of apoptosis and inhibition of cell proliferation to the modulation of crucial signaling pathways. These natural compounds exhibit promising anticancer potential by targeting key facets of cancer progression, notably by i) instigating apoptosis and ii) intervening in cell cycle checkpoints. However, a more strategic and nuanced investigation is imperative to fully elucidate their optimal dosages, modes of action, and potential synergies with existing cancer treatment modalities. This critical gap in our understanding underscores the necessity for further in-depth research to optimize the therapeutic potential of these plant-derived chemicals.

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Assessment of Dose Calibrators Performance in Nuclear Medicine Department in Sudan

Cited by 2 publications

References 1 publication

Comparative Assesment of Dose Calibrators Used in Nuclear Medicine

Comparative Assesment of Dose Calibrators Used in Nuclear Medicine

Comprehensive Review on Mechanistic Insights, Optimal Dosages, and Safety Prospective of Natural Products in Anticancer Therapeutics

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