Assessment of diastolic myocardial function in neonates with patent ductus arteriosus using tissue Doppler imaging

Abstract

Background: The present study was an analytic case control study was done and included full and preterm neonates with PDA and respiratory distress. Neonates with no PDA were also included as a control. Aim of the study: This study aimed to assess diastolic myocardial functions in neonates with different degrees of ductal patency in 1st week of life using tissue Doppler imaging. Methods: The study was conducted at neonatal intensive care unit (NICU) in Bab-Sheria hospital, pediatric department, faculty of medicine, Al Azhar University in the period from June 2018 to June 2021. The present work was conducted on fifty Neonates categorized into 3 groups as follow: Haemodynamically significant dusctus arteriosus cases: ductal diameter more than 2.5 mm and left atrium to aorta (LA: AO) ratio more than 1.5. Non haemodynamically significant ductus arteiosus cases: ductal diameter less than 2.5 mm or (LA: AO) ratio less than 1.5 and Non patent dusctus arteriosus ( Control group). Results: Amount of left-to-right shunt will increase according to the size of the systemic-to-pulmonary communication, and it results in an increased pulmonary blood flow which agrees with our study.