Assessment of diabetic retinopathy and diabetes management systems in Pakistan using a WHO  tool

Afghani, Tayyab; Khan, Samina Bano; Mansoor, Hassan; Nisar, Sana; Waseem, Shehzad

doi:10.5455/jpma.12450

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, recent surveys and reports suggest that around 10 to 91 percent of individuals with diabetic retinopathy are among all patients with diabetes. 8 One of the factors associated with the development of DR includes coagulation profile disruption. This has recently gained importance.…”

Section: Introductionmentioning

confidence: 99%

Coagulation Profile in Diabetes and Its Association with Diabetic Microvascular Complications

Khan

Rauf²,

Khan³

et al. 2023

PAFMJ

View full text Add to dashboard Cite

Objective: To investigate the hemostatic parameters and to assess their relationship with microvascular complications in patients with type-2 diabetes mellitus. Study Design: Comparative cross-sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi Pakistan, from Jul to Dec 2020. Methodology: Patients with type-2 diabetes aged 40-70 years of both genders were included. We included sixty subjects with diabetes and sixty healthy individuals. HBA1c, prothrombin time, activated partial thrombin time, and fibrinogen levels were measured in both groups, and retinal photographs were taken. Results: The platelet count was in the normal range for both groups but significantly lower in cases compared to controls (177.5±18.3 vs 231.2±18.1, p<0.001). Similarly, the mean fibrinogen level was significantly higher among cases compared to controls (298.2±11.4 vs 256.6±6.5, p<0.001). No significant difference was found between mean prothrombin time and activated partial thromboplastin time among the groups. Most complicated cases belonged to the group with more than 7% glycosylated haemoglobin compared to non-complicated cases (p<0.001). A significant association between the level of HBA1c and diabetic retinopathy was found. Conclusion: The study showed that with a rise in glycemic index, the coagulation profile derangement occurs, with an increase in fibrinogen levels, decrease in platelets count and increase in microvascular complications.

show abstract

Section: Introductionmentioning

confidence: 99%

Coagulation Profile in Diabetes and Its Association with Diabetic Microvascular Complications

Khan

Rauf²,

Khan³

et al. 2023

PAFMJ

View full text Add to dashboard Cite

show abstract

“…Even though recent advances have been occurring, DR screening is a large unmet need also among other countries where enormous contingents of individuals with diabetes dwell (4), as is the case of the United States, where less than half of such individuals adhere to eye screening guidelines (5,17), and also of other low to middle income countries, where the availability of screening programs and adherence rates are even lower (4,(18)(19)(20)(21). In this sense, the study by Yao Yang and collaborators is very relevant not only for the local setting, but on a global scale.…”

mentioning

confidence: 99%

Artificial intelligence for diabetic retinopathy screening: beyond diagnostic accuracy

Malerbi¹

2022

Ann Transl Med

View full text Add to dashboard Cite

“…Sufficient large study data are available in most of the South-East Asia countries on the prevalence of DR, and they have established their national plans to preventer burden. [ 8 ] However, in Pakistan, the burden of vision loss from DM is not clear,[ 9 ] evaluation of DR in diabetic patients is not normally carried out, and there are insufficient studies on prevalence of DR.[ 9 10 ] In a recent systematic review on the prevalence of DR in Pakistan by Mumtaz SN et al ,[ 9 ] the pooled prevalence of DR was found to be 28.78% with very wide variation from 10.6% to 91.3%. [ 9 ] Reliable population-based data and particularly data from rural areas for the prevalence of DR are lacking.…”

mentioning

confidence: 99%

Prevalence of diabetic retinopathy in rural Pakistan: A population based cross-sectional study

Jokhio

Talpur

Shujaat

et al. 2022

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose: To estimate the prevalence of diabetic retinopathy (DR), an emerging cause of sight threat and blindness from a large rural population in Pakistan. Methods: This was a population-based cross-sectional study. We selected a rural district of Matiari Sindh Province in Pakistan, where we selected all the health facilities and their attached Lady Health Workers (LHWs)/Lady Health Supervisors (LHSs). These female health workers were trained to identify high-risk diabetic individuals in their catchment areas using pre-defined criteria and to refer them to the nearest health facilities for screening and testing random blood sugar (BSR). Adults of 18 years or above, male or female, were included in the study for DM and DR screening. Ophthalmic examination was conducted by the optometrists on those who had BSR level >180 mg/dl for the evidence of DR. Identified DR patients were referred to a linked tertiary-level ophthalmology institute for their free DR treatment. Results: Of the identified and referred 24,463 participants, 23,999 were tested for BSR and 2,331 (9.74%) were found to be high-risk patients (BSR >180 mg/dl) and had ophthalmic examination conducted. Of these, 563 had clinically established DR, a prevalence of 24.2% (95% CI, 22–26%). Significantly more DR patients (228, 40.5%) were found in the age group >60 years, with more among female (327, 58.1%) with DR. Conclusion: DR is highly prevalent in the Pakistani rural population. The establishment of an integrated approach within the health care system could decrease the burden of DR in Pakistan.

show abstract

Assessment of diabetic retinopathy and diabetes management systems in Pakistan using a WHO tool

Cited by 3 publications

References 0 publications

Coagulation Profile in Diabetes and Its Association with Diabetic Microvascular Complications

Coagulation Profile in Diabetes and Its Association with Diabetic Microvascular Complications

Artificial intelligence for diabetic retinopathy screening: beyond diagnostic accuracy

Prevalence of diabetic retinopathy in rural Pakistan: A population based cross-sectional study

Contact Info

Product

Resources

About