Assessment of Depression and Anxiety in Patients with Chronic Kidney Disease and after Kidney Transplantation—A Comparative Analysis

Dziubek, Wioletta; Pawlaczyk, Weronika; Rogowski, Łukasz; Stefańska, Małgorzata; Gołębiowski, Tomasz; Mazanowska, Oktawia; Krajewska, Magdalena; Kusztal, Mariusz; Kowalska, Joanna

doi:10.3390/ijerph181910517

Cited by 11 publications

(8 citation statements)

References 26 publications

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“…This could suggest that non-MS HD patients benefit more in terms of reducing the severity of trait anxiety (X2) compared to patients with metabolic syndrome. This may be clinically relevant because, as shown in other studies [64], trait anxiety (X2) is most strongly associated with depressive symptoms.…”

Section: Discussionmentioning

confidence: 65%

Metabolic Syndrome and Psychological Effects of Exercise in Hemodialysis Patients

Hornik

Duława

Durmała

2021

IJERPH

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Metabolic syndrome (MS) and anxiety disorders are common problems among hemodialysis patients (HD). However, there have been no studies defining the role of physical activity in reducing anxiety in HD patients with MS. This study was aimed to determine the effects on the severity of anxiety of a four-week rehabilitation program for HD patients, with or without metabolic syndrome (MS), planned and adapted to their abilities. The study was single-center, interventional, non-randomized, and prospective. Fifty-eight individuals completed the project (28 HD patients and 30 controls (C) with normal kidney function). Each group was divided into two subgroups with respect to MS. The mean age of the subjects in the HD and C groups was 56.9 ± 13.3 years (x¯ ± SD) and 61.5 ± 8.3 years (x¯ ± SD), respectively. Planned and adapted to the patient’s abilities, the rehabilitation program based on physiotherapy was provided to each subject for 4 weeks. Baseline and post-intervention determined anxiety levels using the State-Trait Anxiety Inventory (STAI). The X1 scale tests state anxiety, and the X2 scale tests trait anxiety. Post-intervention, there was no significant difference in the intensity of state anxiety observed in HD patients compared to C with normal renal function, as observed before the program. After four weeks of regular physical activity planned and adapted to the patient’s abilities in an inpatient ward, the level of state anxiety (X1) and trait anxiety (X2) lowered considerably in all HD patients (respectively: 35.1 ± 8.0 vs. 29.2 ± 5.0, p = 0.001 for X1 and 41.8 ± 9.1 vs. 38.1 ± 5.9, p = 0.008 for X2). The rehabilitation program significantly reduced the intensity of state anxiety (X1) in HD patients with MS (35.8 ± 7.9 vs. 29.2 ± 5.1; p = 0.01). The rehabilitation program helped to significantly reduce the intensity of trait anxiety (X2) in HD patients without MS (41.9 ± 10.7 vs. 36.9 ± 5.9; p = 0.04). Four-week physical activity planned and adapted to the patient’s abilities reduces the intensity of anxiety in HD patients and controls with normal renal function. HD patients with MS benefit more in terms of reducing perceived state anxiety, and HD patients without MS in terms of reducing trait anxiety.

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Section: Discussionmentioning

confidence: 65%

Metabolic Syndrome and Psychological Effects of Exercise in Hemodialysis Patients

Hornik

Duława

Durmała

2021

IJERPH

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“…Tsai et al, Lee et al, and Danielle et al reported clinical depression levels of 37% [ 59 ], 47.1% [ 60 ], and 40% [ 61 ], respectively, for CKD Stages III, IV, and V. Generally, patients with CKD (Stage V) displayed the highest prevalence of clinical depression [ 55 ]; however, this finding was inconsistent. Dziubek et al revealed a 53% prevalence of depression among patients with Stage V renal failure [ 62 ]. In this study, high levels of depression were not surprising because of the lack of quality support (financial, social, and medical), also reported by Hettiarachchi and Abeysena [ 63 ].…”

Section: Discussionmentioning

confidence: 99%

Depression among patients with chronic kidney disease, associated factors, and predictors: a cross-sectional study

Bahall,

Legall,

Lalla

2023

BMC Psychiatry

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Background Depression with diverse etiologies is exacerbated by chronic diseases, such as chronic kidney disease (CKD), coronary artery disease (CAD), cancer, diabetes mellitus, and hypertension. This study aimed to analyse depression, its associations, and predictors among patients attending the kidney clinic of a teaching hospital. Methods Data were collected from 01 August 2017 to 30 September 2017 via face-to-face interviews and examination of the medical records of a convenience sample of 314 patients. The patients were categorised broadly as stages I and II with an estimated glomerular filtration rate (eGFR) > 60 mls/min/1.73 m2, and with stages III, IV, and V or GFR ≤ 60 mls/ min/1.73 m2 (or CKD). The Patient Health Questionnaire (PHQ)-9 was the data collection instrument for depression-related data. Results Participants were predominantly male (n = 179; 57.0%), aged over 60 years (n = 211; 67.2%), Indo-Trinbagonian (n = 237; 75.5%), and with stages III, IV, and V CKD. The two leading comorbid conditions were hypertension (83.4%) and diabetes mellitus (56.1%). Of the 261 (83.1%) patients with recorded eGFR, 113 (43.3%) had Stage III CKD. The mean depression (PHQ-9) score was 13.0/27 ($$\pm$$9.15), with 306 (97.5%) patients diagnosed as having depression with the following severities: mild (n = 116; 37.9%), moderate (n = 138, 45.1%), moderately severe (n = 38; 12.4%), and severe (n = 14; 4.6%). Depression was independent of sex. Nine sociodemographic variables were associated with depression; however, ‘level of education’, was the only predictor of depression with greater severity associated with lower levels of education. eGFR was negatively correlated with the PHQ-9 scores (Pearson’s correlation, r = -0.144, p = 0.022). At least 78.3% of the patients who self-reported no depression had clinical depression (moderate, moderately severe, or severe) PHQ-9 scores ≥ 10. Conclusion Depression was a significant comorbidity among patients with CKD, with the majority displaying clinical depression. “Level of education” was the only predictor of depression. Self-reported depression is an unreliable method for evaluating clinical depression.

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“… 11 The diagnose of depression in ESRD patients is challenging due to the overlap of the main somatic symptoms of the depression, such as anorexia, fatigue and sleep disturbances, with those of ESRD, 12 , 13 leading to delays in diagnosis and treatment. 14 Early and appropriate diagnosis of depression in ESRD patients is crucial for improving treatment adherence and quality of life. 14 , 15 Therefore, health care professional caring for HD patients should be qualified to regularly assess and investigate depression, facilitating promptly referral to psychologists for early treatment.…”

Section: Introductionmentioning

confidence: 99%

“… 14 Early and appropriate diagnosis of depression in ESRD patients is crucial for improving treatment adherence and quality of life. 14 , 15 Therefore, health care professional caring for HD patients should be qualified to regularly assess and investigate depression, facilitating promptly referral to psychologists for early treatment. 3 , 5 Recent studies highlight the positive impact of early nursing screening, psychological support, and nursing intervention in the treatment compliance, quality of life, and the reduction of anxiety, depression and risk of complications.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

Alkubati,

Al-Sayaghi,

Salameh

et al. 2024

JMDH

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Background Depression has a negative impact on the health outcomes of hemodialysis (HD) patients, including decreased quality of life and increased morbidity and mortality rates. Therefore, this study aimed to determine the prevalence of depression and its associated factors among HD patients in Hodeida city, Yemen. Methods A cross-sectional study involving 200 HD patients at the Dialysis Center in Hodeida was conducted from February to May 2022. Data on depression were collected using the 9-item Patient Health Questionnaire (PHQ-9). Association of sociodemographic characteristics of patients with depression were assessed using chi-square, subsequently by multivariable logistic regression. Statistical significance was set at P -values <0.05. Results The response rate was 98% (200/204). Depression was prevalent among 63% of HD patients at the Dialysis Center in Hodeida city. Sex was significantly associated with depression, where female patients were more frequently depressed than males (82.4% vs 56.4%, P < 0.001). In addition, employment status and medical insurance were significantly associated with depression, where unemployed patients were more frequently depressed than employed patients (67.6% vs 52.5%, P = 0.041) and patients with medical insurance were less frequently depressed than their counterparts (47.1% vs 66.3%, P = 0.035). Conclusion Depression is highly prevalent among HD patients in Hodeida city. Female sex, unemployment and lack of medical insurance are predictors of depression among HD patients. These findings emphasize the urgent need for targeted interventions. Implications for practice Depression is common among HD patients, so that, psychiatric physicians and nurses are increasingly needed in HD centers to implement mental health assessment of patients for depression signs and symptoms to help in early diagnosis and management of depression in order to improve patients’ quality of life and preventing negative outcomes.

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Assessment of Depression and Anxiety in Patients with Chronic Kidney Disease and after Kidney Transplantation—A Comparative Analysis

Cited by 11 publications

References 26 publications

Metabolic Syndrome and Psychological Effects of Exercise in Hemodialysis Patients

Metabolic Syndrome and Psychological Effects of Exercise in Hemodialysis Patients

Depression among patients with chronic kidney disease, associated factors, and predictors: a cross-sectional study

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

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