Assessment of Critical Exposure Pathways

Clark, Kathryn; Cousins, Ian T.; Mackay, Donald

doi:10.1007/b11468

Cited by 68 publications

(57 citation statements)

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“…Additionally, other chemical exposures found in the human environment are also suspected of being endocrine-disrupting obesogens. As an example, diet is also thought to be the primary route of exposure to phthalates (14,15) , which are often added to food packaging materials to increase flexibility and resilience (15,(97)(98)(99)(100) . Phthalate exposure has also been associated with increased risk of obesity (49,101,102) .…”

Section: Discussionmentioning

confidence: 99%

Bisphenol A exposure and associations with obesity among adults: a critical review

Oppeneer

Robien

2014

Public Health Nutr.

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Objective: To review the literature on bisphenol A (BPA) exposure and obesity in human populations. Design: Systematic review of the literature via searches of PubMed, EMBASE, Web of Science and reference lists for articles published to 1 August 2014. Setting: China, Italy, Japan, Republic of Korea, Sweden, UK, USA. Subjects: Adults (≥18 years). Results: Eighteen articles were identified and included in the review. Twelve studies included secondary evaluations of BPA exposure and BMI, and six studies evaluated body composition as the primary outcome. All analyses were crosssectional and no study included in the review received a positive quality rating (twelve negative, six neutral). Eight studies observed a statistically significant positive association between urinary or serum BPA levels and BMI, and ten studies observed no association. Studies where BMI was a primary outcome and studies of neutral quality were more likely to observe an association. Conclusions: Study results are conflicting and significant methodological issues limit the ability to draw conclusions from these studies. Prospective studies that measure BPA exposure and changes in body weight and composition are needed to establish temporality, causality and the direction of any observed associations.

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Section: Discussionmentioning

confidence: 99%

Bisphenol A exposure and associations with obesity among adults: a critical review

Oppeneer

Robien

2014

Public Health Nutr.

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“…Researchers say they are constantly being released into the environment through migration, evaporation, leaching and abrasion from consumer products (Wittasek et al 2011, p. 8). The primary route of human exposure to phthalates is through food contaminated as the chemicals migrate from plastic packaging (Kohn et al 2000, Clark et al 2003, Colacino et al 2010. Additional routes of exposure include inhalation of fragrances, hair sprays, and cleaning products and dermal absorption from handling toys and other items.…”

Section: The Ubiquity Of Everyday Toxicsmentioning

confidence: 99%

‘Wannabe Toxic-Free?’ From precautionary consumption to corporeal citizenship

Scott

Haw

Lee

2016

Environmental Politics

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Ecological citizens are increasingly encouraged to adopt 'precautionary consumption' -a set of practices aimed at shielding them from the potential health harms of exposures to everyday toxics. The utility and the effects of precautionary consumption in relation to common chemical exposures are investigated. Precautionary consumption is not only of questionable utility, but is fundamentally misguided as an approach for inspiring antitoxics organizing. The failure of this approach is in part due to its assumption of a naturally bounded, autonomous individual who is able to maintain an impermeable boundary between herself and the environment. Drawing on the work of material feminist theorists, it is argued that Gabrielson and Parady's notion of corporeal citizenship, an approach that places bodies into a complex web of material, ecological relations entangled with the social, offers several strategic advantages for framing resistance strategies.

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“…Moreover, since DEHP is omnipresent in the environment contamination can easily occur during analytical procedures . Finally, one has to consider that the calculated DEHP exposure via food might be based on outdated DEHP contents in food or that the DEHP burdens have not been corrected for background contamination (Clark et al 2003a), which would lead to an overestimation of the DEHP exposure. The range of DEHP exposure in the general population from all sources excluding medical and occupational exposure has been estimated to be 1 to 30 µg/kg bw/d (CERHR 2005, Doull et al 1999, Huber et al 1996.…”

Section: Metabolism Of Dehp In Humansmentioning

confidence: 99%

Plasticizer concentration in cord blood cryopreserved with DMSO

Yamaguchi

Takanashi

Ito

et al. 2013

Bone Marrow Transplant

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The Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) has evaluated the exposure to DEHP for the general population and patients during medical procedures. In many cases the exposure is significant and exceeds the toxic doses observed in animal studies. There is limited evidence indicating a relation between DEHP exposures and certain effects in humans. However, it is recognised that especially the potentially high exposure during medical treatments raise a concern, even in the absence of clinical or epidemiological evidence, for harmful effects in humans. For certain uses of DEHP alternative plasticizers for PVC are available. The Committee got access to toxicity data for eight possible alternative plasticizers and compared their toxicity with that of DEHP. In respect to reproductive toxicity in animal studies DEHP induces more severe effects compared with some of the alternatives. A risk assessment of these available alternative plasticizers could not be performed due to a lack of exposure data from medical devices. Each alternative to DEHP, however, must also be evaluated with regard to their functionality in respect to medical devices. The risk and benefits of using alternative plasticizers should be evaluated case by case.

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Assessment of Critical Exposure Pathways

Cited by 68 publications

References 0 publications

Bisphenol A exposure and associations with obesity among adults: a critical review

Bisphenol A exposure and associations with obesity among adults: a critical review

‘Wannabe Toxic-Free?’ From precautionary consumption to corporeal citizenship

Plasticizer concentration in cord blood cryopreserved with DMSO

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