Assessment of cortical gyrus and sulcus formation using MR images in normal fetuses

Abe, Seiji; Takagi, Kenjiro; Yamamoto, Tatsuo; Okuhata, Yoshitaka; Kato, Tadaya

doi:10.1002/pd.561

Cited by 28 publications

(23 citation statements)

References 18 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In research into the cerebral effects of prematurity, qualitative scales of gyration have normally been used to estimate the cerebral maturation of the fetuses or the premature newborn. 7 Scales of this kind have generally been useful for identification of cerebral maturation stage, detection of major neurologic abnormalities, and prediction of neurologic outcomes of preterm newborns, but they are unable to determine mild cerebral dysfunctions. Using a whole-cortex convolution index, a previous study found that preterm infants significantly differed from controls born at term.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Abnormal orbitofrontal development due to prematurity

Giménez

Junqué²,

Vendrell³

et al. 2006

Neurology

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

“…However, MRI has become an important source for identifying sulci and gyral abnormalities. [6][7][8][9][10][11][12][13][14][15] Magnetic resonance (MR) studies demonstrated that brain maturation starts in the central area and proceeds toward the parieto-occipital cortex. The frontal cortex develops last.…”

mentioning

confidence: 99%

Abnormal orbitofrontal development due to prematurity

Giménez

Junqué²,

Vendrell³

et al. 2006

Neurology

View full text Add to dashboard Cite

show abstract

“…In this context, one must carefully evaluate which gyral landmarks are established early enough in cortical development to allow their reliable identification throughout different stages of gyrification. For example, the medium and inferior temporal sulci appear around 34 w PMA (Abe et al, 2003) and are therefore not defined at an age where MR scans of preterm infants may be analyzed. Recent approaches have investigated the feasibility of DTI parcellation in adults (Klein et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI

Mewes

Zöllei

Hüppi³

et al. 2007

NeuroImage

View full text Add to dashboard Cite

Regional investigations of newborn MRI are important to understand the appearance and consequences of early brain injury. Previously, regionalization in neonates has been achieved with a Talairach parcellation, using internal landmarks of the brain. Non-synostotic dolichocephaly defines a bi-temporal narrowing of the preterm infant's head caused by pressure on the immature skull. The impact of dolichocephaly on brain shape and regional brain shift, which may compromise the validity of the parcellation scheme, has not yet been investigated. Twenty-four preterm and 20 fullterm infants were scanned at term equivalent. Skull shapes were investigated by cephalometric measurements and population registration. Brain tissue volumes were calculated to rule out brain injury underlying skull shape differences. The position of Talairach landmarks was evaluated. Cortical structures were segmented to determine a positional shift between both groups. The preterm group displayed dolichocephalic head shapes and had similar brain volumes compared to the mesocephalic fullterm group. In preterm infants, Talairach landmarks were consistently positioned relative to each other and to the skull base, but were displaced with regard to the calvarium. The frontal and superior region was enlarged; central and temporal gyri and sulci were shifted comparing preterm and fullterm infants. We found that in healthy preterm infants, dolichocephaly led to a shift of cortical structures, but did not influence deep brain structures. We concluded that the validity of a Talairach parcellation scheme is compromised and may lead to a miscalculation of regional brain volumes and inconsistent parcel contents when comparing infant populations with divergent head shapes.

show abstract

“…This classification focuses on frontal and occipital sulcation and gyration, observing the folds of the insular cortex at the stage 4 only (37-39 GWs). The development of the cerebral cortex was later classified into eight stages using MR images in the Ac-Pc plane, with special attention to the frontal and temporal lobes (Abe et al 2003).…”

Section: Chronological Classification Of Macroscopical Developmentmentioning

confidence: 99%

Development of the human fetal insular cortex: study of the gyration from 13 to 28 gestational weeks

et al. 2007

View full text Add to dashboard Cite

To describe the morphological stages of insular sulci and gyri development we carried out a macroscopical study on 21 human fetal brains, showing no anomalies, from 13 to 28 gestational weeks (GWs). Particular focus was given to morphological appearance during the development of insular and periinsular structures, especially the gyration and sulcation of the insula, central cerebral region and opercula, as well as the vascularization of these regions. The periinsular sulci and the central (insular and cerebral) sulci were the first macroscopical structures identified on the lateral surface of the human fetal cerebral hemisphere with earlier development on the right hemisphere. Here we describe five stages of insular gyral and sulcal development closely related to gestational age: stage 1: appearance of the first sulcus at 13-17 GWs, stage 2: development of the periinsular sulci at 18-19 GWs, stage 3: central sulci and opercularization of the insula at 20-22 GWs, stage 4: covering of the posterior insula at 24-26 GWs, stage 5: closure of the sylvian fissure at 27-28 GWs. We provide evidence that cortical maturation (sulcation and gyration) and vascularization of the lateral surface of the brain starts with the insular region, suggesting that this region is a central area of cortical development.

show abstract

Assessment of cortical gyrus and sulcus formation using MR images in normal fetuses

Abstract: Our classification is useful for the assessment of fetal cerebral maturation during the third trimester of pregnancy and may contribute to the prenatal diagnosis of developmental delay of the gyrus and sulcus formation.

Cited by 28 publications

References 18 publications

Abnormal orbitofrontal development due to prematurity

Abnormal orbitofrontal development due to prematurity

Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI

Development of the human fetal insular cortex: study of the gyration from 13 to 28 gestational weeks

Contact Info

Product

Resources

About