“…caused by both plant extracts may be due to reducing effects on mediators, macrophages and eosinophils, also to its hepatoprotective effect and inhibitory effect on oogram pattern. PZQ had a moderate effect on granuloma PR after 5wk PI, but PZQ has a week effect on inflammatory mediator's level with a number of worms and eggs at infection time (Botros et al, 2000;. This agreed with Massoud et al (2000c; studied effect of Myrrh on S. mansoni-infected mice liver, with marked reduction of granulomas number and size and significant reduction in collagen content deposition in portal areas and around central veins proving its efficiency.…”