Assessment of collateralized myocardium with Cardiac Magnetic Resonance (CMR): Transmural extent of infarction but not angiographic collateral vessel filling determines regional function and perfusion in collateral-dependent myocardium

Muehling, Olaf; Jerosch‐Herold, Michael; Cyran, Clemens C.; Huber, Armin; Schoenberg, Stefan O.; Reiser, Maximilian; Steinbeck, Gerhard; Näbauer, Michael

doi:10.1016/j.ijcard.2006.08.036

Cited by 13 publications

(4 citation statements)

References 31 publications

(31 reference statements)

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“…Baks et al (18) demonstrated that the TEI present before PCI predicted the likelihood of later improvement in absolute wall thickening, whereas in patients with a CTO, Muehling et al (36) found an inverse correlation between TEI and regional wall thickening, as well as both hyperemic and resting MBF at baseline. Our study confirmed the findings of both studies and, furthermore, is the first to quantify and relate changes in myocardial thickening, blood flow, and irreversible injury before and after CTO PCI.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Treatment of Chronic Total Coronary Occlusions Improves Regional Hyperemic Myocardial Blood Flow and Contractility

Cheng

Selvanayagam

Jerosch‐Herold

et al. 2008

JACC: Cardiovascular Interventions

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110

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Section: Discussionmentioning

confidence: 99%

Percutaneous Treatment of Chronic Total Coronary Occlusions Improves Regional Hyperemic Myocardial Blood Flow and Contractility

Cheng

Selvanayagam

Jerosch‐Herold

et al. 2008

JACC: Cardiovascular Interventions

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110

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“…The small sample size may explain the paradox in this study: it did show an association between an increase in collateral supply and a decrease in the ratio of transmural to nontransmural match. In a small study using CMR [31], no association was detected between collateral supply and extent of viability. More recently, Choi et al, in a study that looked at ECG evidence of myocardial infarction in relation to CTOs and CMR DE, suggested that collateral supply did correlate with viability [23].…”

Section: Collateral Circulation and Viabilitymentioning

confidence: 86%

The relationship between the contralateral collateral supply and myocardial viability on cardiovascular magnetic resonance: Can the angiogram predict functional recovery?

Gosling

Bhatia

Peebles

et al. 2014

International Journal of Cardiology

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“…It was found to be a stronger predictor of collateral-dependent myocardium than the myocardial perfusion reserve. 47 Furthermore, the delay of contrast arrival was related to angiographic collateral vessel filling but seems mostly independent of blood flow. In contrast, perfusion at rest was not different in regions with good or poor angiographic collateral vessel filling.…”

Section: Collateral Circulationmentioning

confidence: 98%

“…In contrast, perfusion at rest was not different in regions with good or poor angiographic collateral vessel filling. 47 Thus, MR perfusion imaging allows the detection of collateraldependent myocardium and adds fundamental and complementary information to standard angiography of collateral vessels.…”

Section: Collateral Circulationmentioning

confidence: 99%

Stress Perfusion Magnetic Resonance Imaging of the Heart

Jerosch‐Herold¹,

Muehling²

2008

Topics in Magnetic Resonance Imaging

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Extensive research has documented that rapid imaging during the first pass of a magnetic resonance imaging (MRI) contrast agent provides good sensitivity to detect myocardial blood flow deficits caused by coronary disease, cardiomyopathies, or microvascular dysfunction in patients without obstructive lesions in the coronary arteries. The autoregulatory mechanisms of the coronary circulation serve the purpose of maintaining sufficient blood flow at baseline in the presence of flow-obstructing coronary lesions. Stress testing is most commonly used in this setting to determine the hemodynamic effect of coronary lesions in the epicardial arteries when the small-vessel resistance has been minimized by vasodilation. The protocols for perfusion MRI combined with vasodilation have been successfully tested in large patient studies. Besides the absence of any ionizing radiation, MRI offers the advantages of relatively high spatial resolution to detect perfusion defects limited to the inner layer of the heart muscle. Furthermore, MRI can be used for noninvasive quantitative measurements of myocardial blood flow that compare well with invasive measurements with labeled microspheres. Additional useful markers, such as the dynamic distribution volume, the delay in the arrival of the contrast agent in a myocardial region relative to the enhancement in the arterial input, and the capillary permeability-surface area product, may, in the future, further enhance the capabilities to characterize with MRI coronary atherosclerosis, coronary vascular dysfunction, and adaptive mechanisms in the coronary circulation, such as arteriogenesis, that reduce ischemia.

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Assessment of collateralized myocardium with Cardiac Magnetic Resonance (CMR): Transmural extent of infarction but not angiographic collateral vessel filling determines regional function and perfusion in collateral-dependent myocardium

Cited by 13 publications

References 31 publications

Percutaneous Treatment of Chronic Total Coronary Occlusions Improves Regional Hyperemic Myocardial Blood Flow and Contractility

Percutaneous Treatment of Chronic Total Coronary Occlusions Improves Regional Hyperemic Myocardial Blood Flow and Contractility

The relationship between the contralateral collateral supply and myocardial viability on cardiovascular magnetic resonance: Can the angiogram predict functional recovery?

Stress Perfusion Magnetic Resonance Imaging of the Heart

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