Assessment of collagen versus non collagen coated anterior vaginal mesh in pelvic reconstructive surgery: prospective study

Lo, Tsia‐Shu; Cortes, Eileen Feliz M.; Wu, Pei‐Ying; Tan, Yiap Loong; Al-Kharabsheh, Ahlam Mahmoud; Pue, Leng Boi

doi:10.1016/j.ejogrb.2016.01.004

Cited by 10 publications

(11 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Avaulta Plus used in our study is a type of such mesh but coated with porcine collagen. Inflammatory response to macroporous monofilament polypropylene mesh had been described in some studies81920. Elmer et al .…”

Section: Discussionmentioning

confidence: 97%

“…This suggests that the presence of synthetic mesh as a foreign body may prolong the inflammatory phase especially with the collagen-coated mesh. Ultrasound features have proven that degeneration of the collagen barrier may take longer than expected, and integration of collagen-coated mesh could occur up to 1 year8. So, even if the collagen-coated mesh was less integrated in the vaginal wall16, the inflammatory reaction was prolonged which allows one to propose that adverse events such as delayed infection, mesh erosion and even the LUTS observed in clinical setting might depend on the duration of the integration process in the collagen-coated mesh.…”

Section: Discussionmentioning

confidence: 99%

“…However, varieties of LUTS including, de novo overactive bladder89, voiding dysfunction and de novo urinary stress incontinence10 may occur after mesh implantation surgery for POP. It would be difficult to differentiate if the LUTS were brought about by a transient physiologic phenomenon secondary to the surgical procedure or a result of a worrisome reaction to the mesh.…”

mentioning

confidence: 99%

“…Coated-mesh had been developed so as to improve the success of vaginal prolapse repair8 and overcome the graft-related complication such as graft rejection. Studies involving different types of coated-mesh either using dermal or urinary bladder ECM, porcine/bovine collagen had been conducted on different aspects but with the same target as to determine the best and safest mesh implant which is still debatable until now111213.…”

mentioning

confidence: 99%

See 3 more Smart Citations

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Lin

Yusoff

et al. 2016

Sci Rep

Self Cite

View full text Add to dashboard Cite

Our aim is to study the inflammatory response towards the collagen-coated and non-coated polypropylene meshes in rats and the urodynamic investigation post-operatively. Forty-two female Sprague Dawley were divided into 7 groups of 6 rats; Control, Day 7 and 30 for Sham, Avaulta Plus (MPC), Perigee (MP). UDS were taken at days 7 and 30. Mesh with the vagina and bladder wall was removed and sent for immunohistochemical examination. Results showed intense inflammatory reaction on day 7 in the study groups which decreased on day 30. IL-1, TNF-α, MMP-2 and CD31 were observed to decrease from day 7 to day 30. NGF was almost normal on day 30 in all groups. UDS showed no difference in voiding pressure. Both Study and Sham groups had shorter voiding interval (VI) on day 7 but significantly lower in MPC. VI had significantly increased on day 30 in all groups. Voided volume was significantly lower in the mesh groups even when an increase was seen on day 30. In conclusion, the higher levels of IL-1, TNF-α and MMP-2 in collagen-coated polypropylene mesh imply greater inflammation than the non-coated polypropylene mesh. Mesh implantation can lead to shorter voiding interval and smaller bladder capacity.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Lin

Yusoff

et al. 2016

Sci Rep

Self Cite

View full text Add to dashboard Cite

show abstract

“…Mesh coating with collagen has been mainly investigated in animal studies showing positive effects on biocompatibility [38][39][40][41]. However, this approach has not shown convincing results for the treatment of anterior vaginal wall prolapse when applying it in humans [42,43].…”

Section: Discussionmentioning

confidence: 99%

Protocol for a Randomized Phase II Trial for Mesh Optimization by Autologous Plasma Coating in Prolapse Repair: IDEAL Stage 3

et al. 2017

View full text Add to dashboard Cite

Introduction: Mesh-related complications especially after vaginal implantation have raised awareness lately because of severe adverse reactions and legal aspects. About 20% of patients suffer from complications after mesh insertion in the anterior vaginal wall. Autologous plasma coating of meshes prior to implantation has shown potential to improve the biocompatibility of meshes in vivo and in vitro. This inno-

show abstract

Transvaginal uterosacral ligament hysteropexy versus hysterectomy plus uterosacral ligament suspension: a matched cohort study

Milani

Manodoro²,

Cola

et al. 2019

Int Urogynecol J

View full text Add to dashboard Cite

Assessment of collagen versus non collagen coated anterior vaginal mesh in pelvic reconstructive surgery: prospective study

Cited by 10 publications

References 24 publications

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Protocol for a Randomized Phase II Trial for Mesh Optimization by Autologous Plasma Coating in Prolapse Repair: IDEAL Stage 3

Transvaginal uterosacral ligament hysteropexy versus hysterectomy plus uterosacral ligament suspension: a matched cohort study

Contact Info

Product

Resources

About