Assessment of Clay Mineral Attenuation Capacity for Human Viral Pathogens

Das, Partha; Bharat, Tadikonda Venkata

doi:10.1061/(asce)hz.2153-5515.0000643

Cited by 3 publications

(3 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bentonites and kaolin are used in many engineering and science applications due to the presence of high percentages of montmorillonite and kaolinite minerals, respectively. These clays are very popular for effectively adsorbing inorganic metals, heavy metals, radioactive elements, proteins, DNA, RNA, some human viral pathogens, and bacteriophages. − The interaction between the clay mineral and the virus surface is governed by factors such as the pH of the solution, ionic strength of solution, and nature of the RNA nucleic acid base. , The adsorption of virus protein onto the clay surface involves various physical and chemical interactions such as hydrogen bonding, electrostatic interactions, van der Waal forces, hydrophilic and hydrophobic interactions, and cation bridging. ,, …”

Section: Introductionmentioning

confidence: 99%

“…Due to the inability to seal macrovoids in granular bentonite of geosynthetic clay liners (GCLs), , there are possibilities for advection dominant virus migration through GCLs in a leachate environment. Although, limited theoretical studies and molecular dynamics simulations on the fate and transport of viral pathogens through clays have recently been available, and experimental studies on virus transport is lacking in providing a scientific rationale for accepting pathogenic waste into MSW landfills. Such studies are also useful for developing pathogenic waste disposal protocols for future epidemics or pandemics.…”

Section: Introductionmentioning

confidence: 99%

“…22,23 The adsorption of virus protein onto the clay surface involves various physical and chemical interactions such as hydrogen bonding, electrostatic interactions, van der Waal forces, hydrophilic and hydrophobic interactions, and cation bridging. 6,24,25 NDV contains hemagglutinin-neuraminidase (HN) and fusion (F) as surface glycoproteins. These surface glycoproteins can potentially be attached to the negatively charged surface of clays (Figure 1).…”

Section: ■ Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fate and Transport of Coronavirus Surrogate through Compacted Clays for Pathogenic Waste Disposal

et al. 2023

View full text Add to dashboard Cite

An increased pathogenic waste post-COVID-19 pandemic forced policymakers to treat biomedical waste (BMW) similar to municipal solid waste (MSW) to dispose into dumpsites and MSW landfills across the globe. The granular bentonite of geosynthetic clay liners (GCLs) does not completely seal the macro-voids upon saturation due to the loss of osmotic potential in the salt environment from the leachate. Such behavior of GCLs can lead to advection-dominant virus migration through the liner system. A knowledge of the fate and transport of coronavirus and other viral pathogens in compacted clays is essential for safe disposal of the viral pathogens in MSW landfills. Although the attenuation and transport parameters for coronavirus have been recently evaluated theoretically, experimental backup is currently lacking. The present work uses Newcastle disease virus (NDV) as a surrogate to coronavirus due to structural similarities for studying the fate and transport in the compacted natural clays. This study also implicitly addresses the waste management facilities for waste generated from NDV outbreaks through poultry litter and carcasses. The interaction of bentonite and kaolin clays with the NDV was studied by varying the virus concentration, interaction time, and clay dose using batch sorption tests. The studied clays showed excellent attenuation efficiency for the NDV. Design parameters, viz., the diffusion coefficient and retardation factor, were evaluated, affirming the suitability of these clays for exclusive pathogenic waste disposal protocols that are discussed in this article.

show abstract