Assessment of Cinnamon as an Antimicrobial Agent

Kiymaci, Merve Eylul; Kaşkatepe, Banu

doi:10.1007/978-3-030-83504-0_4

Cited by 4 publications

(4 citation statements)

References 88 publications

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“…Allicin [ 95 , 96 ], eugenol [ 97 , 98 ], thymoquinone [ 99 ], apigenin [ 100 , 101 ], carvacrol [ 102 , 103 ] and thymol [ 104 ] are some of the most studied metabolites of spice plants with antiviral effects and consequent applications in the efforts to combat COVID-19 ( Table 3 ).…”

Section: Covid 19: Context Treatment and New Drugs Demandmentioning

confidence: 99%

Plant Spices as a Source of Antimicrobial Synergic Molecules to Treat Bacterial and Viral Co-Infections

Duarte

Takahashi

2022

Molecules

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The COVID-19 pandemic exposed the lack of antiviral agents available for human use, while the complexity of the physiological changes caused by coronavirus (SARS-CoV-2) imposed the prescription of multidrug pharmacotherapy to treat infected patients. In a significant number of cases, it was necessary to add antibiotics to the prescription to decrease the risk of co-infections, preventing the worsening of the patient’s condition. However, the precautionary use of antibiotics corroborated to increase bacterial resistance. Since the development of vaccines for COVID-19, the pandemic scenario has changed, but the development of new antiviral drugs is still a major challenge. Research for new drugs with synergistic activity against virus and resistant bacteria can produce drug leads to be used in the treatment of mild cases of COVID-19 and to fight other viruses and new viral diseases. Following the repurposing approach, plant spices have been searched for antiviral lead compounds, since the toxic effects of plants that are traditionally consumed are already known, speeding up the drug discovery process. The need for effective drugs in the context of viral diseases is discussed in this review, with special focus on plant-based spices with antiviral and antibiotic activity. The activity of plants against resistant bacteria, the diversity of the components present in plant extracts and the synergistic interaction of these metabolites and industrialized antibiotics are discussed, with the aim of contributing to the development of antiviral and antibiotic drugs. A literature search was performed in electronic databases such as Science Direct; SciELO (Scientific Electronic Library Online); LILACS (Latin American and Caribbean Literature on Health Sciences); Elsevier, SpringerLink; and Google Scholar, using the descriptors: antiviral plants, antibacterial plants, coronavirus treatment, morbidities and COVID-19, bacterial resistance, resistant antibiotics, hospital-acquired infections, spices of plant origin, coronaviruses and foods, spices with antiviral effect, drug prescriptions and COVID-19, and plant synergism. Articles published in English in the period from 2020 to 2022 and relevant to the topic were used as the main inclusion criteria.

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Section: Covid 19: Context Treatment and New Drugs Demandmentioning

confidence: 99%

Plant Spices as a Source of Antimicrobial Synergic Molecules to Treat Bacterial and Viral Co-Infections

Duarte

Takahashi

2022

Molecules

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“…The increasing microbial resistance to synthetic antimicrobial agents poses a global challenge and the demand for alternative medicines targeting resistant strains is on the rise [3]- [4]. Medicinal and aromatic antimicrobial agents that may be effective against resistant strains are under investigation [5]. The medicinal properties of plants have been passed down from one society to the next for centuries [6].…”

Section: Introductionmentioning

confidence: 99%

An Innovative Approach to Various Industrial Applications: The Fingered Citron

Tasbasi,

Asan-Ozusaglam

2024

Hung. J. Ind. Chem.

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The fingered citron (Citrus medica L. var. sarcodactylis), which originates from India, has spread to different parts of the world over time. In opposition to the increasing resistance to traditional antimicrobial agents, the application of alternative treatments developed using herbs has recently gained interest. The aim of this study is to investigate alternative applications of the fingered citron in the cosmetics and pharmaceutical industries. For this purpose, the antimicrobial activity of fingered citron leaf water extract (FCLWE) against test microorganisms was evaluated using a disk diffusion assay. Minimum inhibitory concentration (MIC) and minimum cidal concentrations (bactericidal - MBC or fungicidal - MFC) of the extract were also determined. For FCLWE, among the pathogenic test microorganisms, Listeria monocytogenes strain ATCC 7644 and Staphylococcus aureus strain ATCC 25923 showed the smallest and the largest inhibition zone diameters, with values of 7.06 and 11.57 mm, respectively. MIC and MBC or MFC values of FCLWE varied from 10 to 40 µg/µl. In addition, the sun protection factors (SPF) of FCLWE and a mixture of FCLWE and commercial sun creams at different concentrations were determined. The SPF value of FCLWE was found to be 25. The mixture of FCLWE and commercial sun cream at an amount of 10 ml yielded an SPF value of 12.26. Next, the biological activity of the cream formulation obtained with commercial cream, FCLWE and Limosilactobacillus fermentum MA-7 (cream-leaf water extract-probiotic - CWP) was investigated against test microorganisms using the well diffusion method. CWP exhibited inhibitory activity against L. monocytogenes ATCC 7644 (2.56 mm), Candida glabrata RSKK 04019 (2.81 mm), C. albicans ATCC 10231 (4.54 mm) and S. aureus ATCC 25923 (5.00 mm). It was observed that the cream formulation of CWP increased the diameters of the inhibition zone by creating a synergistic effect against all pathogenic test microorganisms. FCLWE may potentially be used as an alternative natural additive to chemical preservatives in the cosmetics and pharmaceutical industries.

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“…Bacteria have the ability to cross-transmit antibiotic resistance, and this resistance can be indirectly transmitted between humans, animals, environments etc. spreads in a chain [3][4][5]. This causes a significant increase in the number of drug-resistant strains worldwide.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, an antimicrobial treatment approach to reduce the virulence of microorganisms has gained importance by developing methods based on aromatic and medicinal plants. In this context, the use of plants, spices and essential oils (EOs) as antimicrobial agents is among the most important researches [5,8].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and antibiofilm activity of Melaleuca alternifolia (tea tree) essential oil against colistin resistant Salmonella enterica serotypes isolated from poultry environmental specimens

KIYMACI¹,

SAVLUK²,

GUMUSTAS³

et al. 2023

jrp

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The development of increasing resistance to antibiotics such as colistin, problems arise in the treatment of bacterial infections and make it necessary to search new alternative methods. For this purpose, plant-based approaches are among the important research topics depending on their traditional uses. The aim of the present study was to investigate the antibacterial and antibiofilm activity of tea tree oil purchased from a local market against a variety of 66 colistin resistant Salmonella enterica serotypes isolated from poultry farm environmental samples. Content analysis of TTO was determined by gas chromatography/mass spectroscopy. The antibacterial activity was determined by broth microdilution method, and antibiofilm activity was examined by crystal violet method. As a result, terpinen-4-ol was found as major component of TTO with 35.9% ratio. The MIC values of TTO were differed between 6250-12500 µg/mL. 27 of 66 isolates formed biofilm and 25 of 27 isolates belonged to S. Infantis. The biofilm reduction of TTO at subinhibitory concentration were found between 52-84.4%. Current study should be supported by future studies to determine the effectiveness of TTO to be among the agents that can be used together with antimicrobials in the attenuation of microorganisms.

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Assessment of Cinnamon as an Antimicrobial Agent

Cited by 4 publications

References 88 publications

Plant Spices as a Source of Antimicrobial Synergic Molecules to Treat Bacterial and Viral Co-Infections

Plant Spices as a Source of Antimicrobial Synergic Molecules to Treat Bacterial and Viral Co-Infections

An Innovative Approach to Various Industrial Applications: The Fingered Citron

Antibacterial and antibiofilm activity of Melaleuca alternifolia (tea tree) essential oil against colistin resistant Salmonella enterica serotypes isolated from poultry environmental specimens

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