Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

Huang, Rae Chi; Prescott, Susan L.; Godfrey, Keith M.; Davis, Elizabeth A.

doi:10.1017/jns.2014.69

Cited by 39 publications

(28 citation statements)

References 90 publications

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“…WC, particulary visceral fat, is an independent risk factor for diabetogenic-atherogenic abnormalities in adolescents [7,8,10,11]. In our study, we found a high percentage of dyslipidemia in obese children.…”

Section: Results and Discusionssupporting

confidence: 56%

Predictive Biological Markers in Post-therapeutic Evolution in Obese Patients

Trandafir¹,

Baciu²,

Constantin³

et al. 2018

Rev. Chim.

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Childhood obesity is a leading public health concern because it represents a risk factor for many comorbid conditions in youth, such as cardiovascular disease, metabolic syndrome and sleep apnea. The purposes of the study were to evaluate the effect of the program at 6 months after the first visit and determine the predictive factors. We realised a retrospective study that included 69 obese children and adolescent, boys and girls, followed-up at Saint Mary Children�s Hospital and Regional Center of Diagnosis, Counselling and Monitoring of Overweight and Obese Children from �Grigore T. Popa� University of Medicine and Pharmacy Iasi, Romania, aged 12 to 18 years. The patients were included in two groups: group 1 included 38 patients receveived a hypocaloric diet only and group 2 included 31 patients received a hypocaloric diet associated with kinetotherapy and psychoterapy. We evaluated the body mass index, total cholesterol and tryglicerides before and after treatment. Our results confirm that diet and physical activity affects significantly the serum lipid profile. In this context, decreasing obesity in children through diet and exercise should be an important strategy for preventing cardio-metabolical disease in adult.

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Section: Results and Discusionssupporting

confidence: 56%

Predictive Biological Markers in Post-therapeutic Evolution in Obese Patients

Trandafir¹,

Baciu²,

Constantin³

et al. 2018

Rev. Chim.

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“…Assessing cardiometabolic risk in children is important as it predicts cardiovascular and metabolic disease later in life . Recognising insulin resistance (IR) in children is a particularly important issue from a public health policy perspective.…”

Section: Introductionmentioning

confidence: 99%

The triglyceride and glucose index is useful for recognising insulin resistance in children

2017

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“…There is steadily accumulating evidence that the intrauterine environment has long-lasting effects on child growth and development (see [16] for just one recent review). We are extensively phenotyping a cohort of children from a randomized controlled trial of high dose prenatal docosahexaenoic acid (DHA) supplementation [17].…”

Section: Introductionmentioning

confidence: 99%

Dietary patterns of early childhood and maternal socioeconomic status in a unique prospective sample from a randomized controlled trial of Prenatal DHA Supplementation

et al. 2016

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BackgroundDietary habits established in early childhood and maternal socioeconomic status (SES) are important, complex, interrelated factors that influence a child’s growth and development. The aim of this study was to define the major dietary patterns in a cohort of young US children, construct a maternal SES index, and evaluate their associations.MethodsThe diets of 190 children from a randomized, controlled trial of prenatal supplementation of docosahexaenoic acid (DHA) were recorded at 6-mo intervals from 2-4.5 years by 24-h dietary recall. Hierarchical cluster analysis of age-adjusted, average daily intake of 24 food and beverage groups was used to categorize diet. Unrotated factor analysis generated an SES score from maternal race, ethnicity, age, education, and neighborhood income.ResultsWe identified two major dietary patterns: “Prudent” and “Western.” The 85 (45%) children with a Prudent diet consumed more whole grains, fruit, yogurt and low-fat milk, green and non-starchy vegetables, and nuts and seeds. Conversely, those with a Western diet had greater intake of red meat, discretionary fat and condiments, sweet beverages, refined grains, French fries and potato chips, eggs, starchy vegetables, processed meats, chicken and seafood, and whole-fat milk. Compared to a Western diet, a Prudent diet was associated with one standard deviation higher maternal SES (95% CI: 0.80 to 1.30).ConclusionsWe found two major dietary patterns of young US children and defined a single, continuous axis of maternal SES that differed strongly between groups. This is an important first step to investigate how child diet, SES, and prenatal DHA supplementation interact to influence health outcomes.Trial registration NCT00266825. Prospectively registered on December 15, 2005Electronic supplementary materialThe online version of this article (doi:10.1186/s12887-016-0729-0) contains supplementary material, which is available to authorized users.

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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

Cited by 39 publications

References 90 publications

Predictive Biological Markers in Post-therapeutic Evolution in Obese Patients

Predictive Biological Markers in Post-therapeutic Evolution in Obese Patients

The triglyceride and glucose index is useful for recognising insulin resistance in children

Dietary patterns of early childhood and maternal socioeconomic status in a unique prospective sample from a randomized controlled trial of Prenatal DHA Supplementation

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