Assessment of cardiac output, intravascular volume status, and extravascular lung water by transpulmonary indicator dilution in critically ill neonates and infants

Schiffmann, Holger; Erdlenbruch, Bernhard; Singer, Dominique; Singer, Sybille; Herting, Egbert; Hoeft, Andreas; Buhre, W.

doi:10.1053/jcan.2002.126954

Cited by 82 publications

(57 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Egan et al [12] measured indexed GEDV in infants (median age 15 months, median weight 9 kg) after cardiac surgery and found mean values of 427 ± 38 ml/m 2 . Similar results for indexed GEDV were reported by Schiffmann et al [30] for critically ill neonates and infants and Lemson et al [17] during pediatric cardiac catheterization. This is approximately two thirds the GEDV considered normal in adults.…”

Section: Discussionsupporting

confidence: 88%

Comparison of Transpulmonary Thermodilution and Ultrasound Dilution Technique: Novel Insights into Volumetric Parameters from an Animal Model

et al. 2012

View full text Add to dashboard Cite

Especially in critically ill children with cardiac diseases, fluid management and monitoring of cardiovascular function are essential. Ultrasound dilution technique (UDT) was recently introduced to measure cardiac output (CO) and volumetric parameters, such as intrathoracic and end-diastolic blood volume. We compared UDT with the well-established transpulmonary thermodilution (TPTD) method (PiCCO) for determining CO measurements and derived volumes in a juvenile animal model. Experiments were performed in 18 ventilated, anesthetized piglets during normovolemia and after isovolemic hemodilution. At baseline and 20 min after each step of isovolemic hemodilution, 3 independent measurements of CO and volumetric parameters were conducted with TPTD and UDT, consecutively, under hemodynamically stable conditions. We observed comparable results for CO measurements with both methods (mean 1.98 l/min; range 1.12-2.87) with a percentage error of 17.3% (r = 0.92, mean bias = 0.28 l/min). Global end-diastolic volume (GEDV) and intrathoracic blood volume (ITBV) by TPTD were almost two times greater than analogous volumes [central blood volume (CBV); total end-diastolic volume (TEDV)] quantified by UDT (CBV = 0.58 × ITBV + 27.1 ml; TEDV = 0.48 × GEDV + 23.1 ml). CO measurements by UDT were found to be equivalent and hence interchangeable with TPTD. Discrepancies in volumetric parameters could either be due to the underlying algorithm or different types of indicators (diffusible vs. nondiffusible). Compared with the anatomically defined heart volume, TPTD seems to overestimate end-diastolic volumes. Future studies will be necessary to assign these results to critically ill children and to validate volumetric parameters with reference techniques.

show abstract

Section: Discussionsupporting

confidence: 88%

Comparison of Transpulmonary Thermodilution and Ultrasound Dilution Technique: Novel Insights into Volumetric Parameters from an Animal Model

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Over time, however, the double indicator technique has been replaced by the transpulmonary single thermal indicator technique, because the latter is relatively noninvasive and easy to perform and has proved to be an accurate means of quantifying extravascular lung water as an index of lung water [14,15] . Moreover, its accuracy is comparable to that of the pulmonary artery thermodilution technique for measuring cardiac output and assessing volume preload parameters in patients with sepsis, acute lung injury, burn shock, coronary artery bypass graft, and liver transplantation, among others [16][17][18][19][20][21][22] .…”

Section: Discussionmentioning

confidence: 99%

Extravascular Lung Water Measured Using Single Transpulmonary Thermodilution Reflects Perioperative Pulmonary Edema Induced by Esophagectomy

Sato

Motoyama²,

Maruyama³

et al. 2006

Eur Surg Res

View full text Add to dashboard Cite

Pulmonary edema is the most frequent postoperative complication following esophagectomy for thoracic esophageal cancer. We enrolled 23 patients who underwent esophagectomy with extended lymph node dissection for thoracic esophageal cancer in a prospective observational clinical trial. We used the PiCCO device to measure extravascular lung water with the aim of determining whether it correlates with the respiratory index and whether it is predictive of pulmonary complications. Based on constant criteria, the tracheal tubes of 11 patients were removed on the morning of postoperative day 1 (extubation group), while 12 patients remained intubated (intubation group). These two groups significantly differed in that all patients in the extubation group recovered without any pulmonary complications, whereas 4 patients (33%) in the intubation group developed pulmonary complications. The extravascular lung water measured using PiCCO correlated significantly with the respiratory index. In the intubation group, both extravascular lung water and respiratory index were elevated 12 h after surgery and were even higher 24 h after surgery. The extravascular lung water measured using PiCCO reflects the level of postoperative pulmonary edema and predicts the pulmonary complications induced by esophagectomy with extended lymph node dissection.

show abstract

“…Femoral arterial thermodilution measurement has been used in infantile animal models and in children [17][18][19][20][21][22][23][24]; it has showed an acceptable correlation with pulmonary arterial thermodilution by using a Swan-Ganz catheter [19,23], and therefore it might be a reliable and less invasive hemodynamic monitoring tool in the post-CA period in children.…”

Section: Cardiovascular Parametersmentioning

confidence: 99%

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

et al. 2010

View full text Add to dashboard Cite

show abstract

Assessment of cardiac output, intravascular volume status, and extravascular lung water by transpulmonary indicator dilution in critically ill neonates and infants

Cited by 82 publications

References 24 publications

Comparison of Transpulmonary Thermodilution and Ultrasound Dilution Technique: Novel Insights into Volumetric Parameters from an Animal Model

Comparison of Transpulmonary Thermodilution and Ultrasound Dilution Technique: Novel Insights into Volumetric Parameters from an Animal Model

Extravascular Lung Water Measured Using Single Transpulmonary Thermodilution Reflects Perioperative Pulmonary Edema Induced by Esophagectomy

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

Contact Info

Product

Resources

About