Assessment of burn wound sepsis by swab, full thickness biopsy culture and blood cuture—A comparative study

Bharadwaj, Renu; Joshi, B. N.; Phadke, S.A.

doi:10.1016/0305-4179(83)90010-4

Cited by 18 publications

(24 citation statements)

References 8 publications

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“…Fifty patients with burns ranging from 30 to 50% TBSA were monitored for clinical signs of sepsis, and only 62.5% had positive burn wound cultures according to surface swabs, compared to 87.5% who had a significant bacterial count on biopsy sample culture. Blood cultures were found to be of only prognostic value in this study (41). Blood cultures have also been shown to be a late sign of invasive burn wound infection even when they are positive (270).…”

Section: Best Approach For Burn Wound Infection Surveillancementioning

confidence: 52%

“…Conflicting results have been obtained by different studies for the following reasons: burn patients do not have homogenous injuries (e.g., the severity and extent of burn injury vary greatly from patient to patient), various sampling techniques and laboratory methods have been used, and most comparative studies were done before the advent of early excision therapy (41,48,247,254,255,282,399,407,408,423). Steer and colleagues (407,408) have reported the largest recent studies that compared the results of surface swab versus biopsy cultures.…”

Section: Best Approach For Burn Wound Infection Surveillancementioning

confidence: 99%

“…Although each of these methods is described for historical completeness, modern burn units universally rely on the collection of surface swabs. Specimens collected by superficial sampling of the burn wound surface must be done after the removal of dressings and topical antibacterial agents and cleansing of the wound surface with 70% alcohol (41,247,407,408).…”

Section: Burn Wound Sampling Techniquesmentioning

confidence: 99%

“…Other investigators have also shown that quantitative burn wound biopsy cultures are more accurate than superficial surface cultures for diagnosing invasive infection in unexcised burn wounds (41). However, tissue biopsy samples must be taken from deep sites beneath the eschar (145).…”

Section: Burn Wound Sampling Techniquesmentioning

confidence: 99%

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Burn Wound Infections

Church

Elsayed

Reid³

et al. 2006

Clin Microbiol Rev

1,584

1,345

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SUMMARYBurns are one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality. Significant thermal injuries induce a state of immunosuppression that predisposes burn patients to infectious complications. A current summary of the classifications of burn wound infections, including their diagnosis, treatment, and prevention, is given. Early excision of the eschar has substantially decreased the incidence of invasive burn wound infection and secondary sepsis, but most deaths in severely burn-injured patients are still due to burn wound sepsis or complications due to inhalation injury. Burn patients are also at risk for developing sepsis secondary to pneumonia, catheter-related infections, and suppurative thrombophlebitis. The introduction of silver-impregnated devices (e.g., central lines and Foley urinary catheters) may reduce the incidence of nosocomial infections due to prolonged placement of these devices. Improved outcomes for severely burned patients have been attributed to medical advances in fluid resuscitation, nutritional support, pulmonary and burn wound care, and infection control practices.

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Section: Best Approach For Burn Wound Infection Surveillancementioning

confidence: 52%

Section: Best Approach For Burn Wound Infection Surveillancementioning

confidence: 99%

Section: Burn Wound Sampling Techniquesmentioning

confidence: 99%

Section: Burn Wound Sampling Techniquesmentioning

confidence: 99%

See 2 more Smart Citations

Burn Wound Infections

Church

Elsayed

Reid³

et al. 2006

Clin Microbiol Rev

1,584

1,345

View full text Add to dashboard Cite

show abstract

“…Surface swabbing gives surface colonization and may not accurately reflect the organism causing wound infection while a count of 105 CFU/gm of tissue in the quantitative assay are likely to develop sepsis and also to predict graft bed receptiveness and safety of wound closure. 15,16 An objective of this study was to emphasize a method of quantitative bacterial assay by tissue biopsy technique for an accurate microbial assessment of burn wound infections and to emphasize the importance of bacterial assay to provide clinical guidelines for reconstructive procedures and to assess the clinical outcome of patients who underwent reconstructive procedures following guidance of quantitative bacterial assay and to predict sepsis by this method and thus aiding its prevention.…”

mentioning

confidence: 99%

The role of quantitative bacteriology on burn wound management

2016

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Wound management in burn centres in the United Kingdom

Papini

Wilson

Steer

et al. 1995

British Journal of Surgery

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Despite advances in the use of topical and parenteral antimicrobial therapy, and the practice of early tangential excision, infection of the burn wound remains a leading cause of morbidity and mortality. The aim of this study was to survey and compare wound management and antibiotic usage in burn surgery in all UK burn centres. A postal questionnaire was used, followed up by telephone. Answers were obtained from all 39 units treating burns in the UK. A written policy on antibiotic usage was used by 13 centres. Excisions were covered routinely by prophylactic antibiotic therapy in 18 units, and three of these used antibiotic cover during all procedures in which the wound was manipulated. No routine antibiotic cover was given in 21 units. All units obtained surface swab cultures, but only two performed punch biopsy of the wounds. Quantitative bacteriology (counting colony forming units) was employed by three centres. Most units cleaned the burn with saline (17 of 39) or chlorhexidine (eight of 39) but combinations of these and other agents were also used. Nearly half (17 of 37) of those who replied had not seen any cases of proven or suspected toxic shock syndrome in the past 2 years. Four units gave prophylaxis against Staphylococcus aureus, and four gave antibiotics against Streptococcus pyogenes, despite recommendations in the literature. Twenty-nine units gave no prophylaxis. This study has revealed that there is no consensus on antibiotic usage amongst centres treating burns in the UK and that most units rely on surface swab cultures to monitor infection.

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Assessment of burn wound sepsis by swab, full thickness biopsy culture and blood cuture—A comparative study

Cited by 18 publications

References 8 publications

Burn Wound Infections

Burn Wound Infections

The role of quantitative bacteriology on burn wound management

Wound management in burn centres in the United Kingdom

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