Assessment of body composition using bioelectrical impedance in patients with schizophrenia – preliminary report

Abstract

SummaryBackground. Metabolic syndrome is found in ~40% of patients treated with antipsychotics and abdominal obesity plays a crucial role in its development. The aim of this study is to evaluate body composition in subjects with schizophrenia treated with antipsychotics. Methods. Anthropometric (BMI, abdominal circumference), laboratory (glucose, lipid profile) and body composition (body fat, lean mass, body water) were measured in 77 patients with schizophrenia. results. Central obesity in women was found in >90% and was more frequent comparing to men (p = 0.04). Incidence of dyslipidemia (~80%) and abnormal body weight (~70%) was also high, while impaired level of blood glucose was less frequent (~25%). Women had more body fat (39.2±1.4 vs. 27.7±1.3, p <0.001) and less lean mass and body water. Comparable energy expenditures combined with lower basal metabolic rate in women may cause higher weight and more body fat. Amounts of excessive body weight and fat were higher in women (13.4±2.1 vs. 8.2±1.5, p = 0.02 and 7.9±1.3 vs. 3.2±1.2, p = 0.008). Percentages of women with weight and body fat exceeding target maximums were higher comparing to men (96.4% vs. 79.6%, p = 0.04 and 89.3% vs. 67.3%, p = 0.03). Conclusions. Treatment with antipsychotics is associated with severe metabolic side-effects. High frequency of abdominal obesity, excessive weight and increased amount of total body fat make women more susceptible to cardiovascular events, thus carefully monitored is required. Assessment of body composition using BIA is an easy and quick method of improving daily psychiatric care.

Investigating Body Mass Index and Body Composition in Patients with Schizophrenia: A Case-Control Study

“…Furthermore, a community-based survey found that individuals with schizophrenia tend to have abdominal obesity, higher fat percentage, and lower muscle mass [14]. Another study found that the body fat was associated with height, weight, BMI, and abdominal and waist circumference, while the basal metabolic rate was associated with age, height, weight, abdominal, and waist circumference among patients with schizophrenia [15]. The inconsistency of factors associated with components of body composition between studies demands further investigations.…”

Assessment of Body Fluid Alteration Using Bioelectrical Impedance in Stroke Patients with Hemiplegia Caused by Cerebral Hemorrhage and Cerebral Infarction

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