Assessment of Blood Loss in Abdominal Myomectomy by Intramyometrial Vasopressin Administration Versus Conventional Tourniquet Application

Saha, Manideepa; Khushboo,; Biswas, Subhash Chandra; Alam, Hajekul; Kamilya, Gouri Sankar; Mukhopadhyay, Madhumita; Mondal, Sarbeswar

doi:10.7860/jcdr/2016/17484.7789

Cited by 16 publications

(32 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6,16,17 No major operative complications were reported in any case of the current study, but transient intra-operative bradycardia was seen in two cases (one in vasopressin group and another in the OA group), they were immediately managed by intra-venous atropine. Surprisingly, the injected medication volume in these two patients was not high compared to many other cases, where the doses was higher due to more and bigger myomata.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A comparative study between the efficacy of local intra-myometrial injection of vasopressin and octreotide acetate, in reducing blood loss during myomectomy

Badawy

2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Symptomatic Uterine leiomyomata may lead to many symptoms including abnormal uterine bleeding, mass pressure effects and infertility. Myomectomy is an option for conservative management, however, it is associated with some disadvantages, mainly increased intra-operative blood loss. Intra-myometrial vasopressin injection during myomectomy is an effective method to decrease the intraoperative bleeding due to its vasoconstrictor effect. Octreotide Acetate (OA) is another vasoconstrictor agent that have not been tested for gynaecologic indications. The current study was conducted to assess the efficacy of local injection of OA in reducing blood loss during conventional abdominal myomectomy, and to compare it with local instillation of vasopressin.Methods: 60 cases with symptomatic leiomyomata were recruited and planned for abdominal myomectomy, they were divided randomly into 3 groups, 20 cases in each. Group I, where local vasopressin was used, group II, where OA was used, and group III (the control group), where no specific medication was used and only free Saline was injected locally.Results: The overall results showed that OA group had significantly less operative time and less blood loss compared to control group. However, when compared to cases in group I, operative time and blood loss were significantly higher. Postoperative haemoglobin levels were significantly lower in group III compared to groups I (P = 0.039) and II (P = 0.044). Blood transfusion was indicated in 9 cases among group III, while only one case needed blood transfusion in group II, and no cases in group I.Conclusions: The use of local intra-myometrial OA is an option for reducing blood loss during myomectomy, but still efficacy is less than local vasopressin. This may be attributed to the low concentrations used, and to the less potency of OA as a vasoconstrictor agent.

show abstract

Section: Discussionmentioning

confidence: 99%

“…It also eliminates the risk of unwanted irreversible ischemic damage to the uterus and thrombo-embolic events of mechanical methods. 6,7 On the other hand, and because it is a potent systemic vasoconstrictor, vasopressin may cause hypertension and bradycardia. It has a plasma half-life of 10-20 minutes.…”

Section: Introductionmentioning

confidence: 99%

A comparative study between the efficacy of local intra-myometrial injection of vasopressin and octreotide acetate, in reducing blood loss during myomectomy

Badawy

2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

“…symptomatic and resistant to medical management or interferes with female reproduction 1,4 . A current management strategy involves surgical intervention depending on the patient's age, the desire for fertility preservation or avoidance of radical surgery, such as hysterectomy 1,5,6 .…”

Section: Bahrain Med Bull 2016; 38(4):204 -207mentioning

confidence: 99%

“…A current management strategy involves surgical intervention depending on the patient's age, the desire for fertility preservation or avoidance of radical surgery, such as hysterectomy 1,5,6 . Myomectomy could be performed abdominally, laparoscopically or by robotic surgeries 1,4,7 .…”

Section: Bahrain Med Bull 2016; 38(4):204 -207mentioning

confidence: 99%

“…Myomectomy is associated with excessive hemorrhage, pyrexia, visceral damage, thrombo-embolism, conversion to hysterectomy, blood transfusions and uterine scar dehiscence 4 . In one study, uterine rupture was found in 2.5% of patients who had a myomectomy, and in another study, no uterine rupture was found in 120 patients 9 .…”

Section: Bahrain Med Bull 2016; 38(4):204 -207mentioning

confidence: 99%

See 1 more Smart Citation

Intra and Postoperative Morbidity Associated with Myomectomy

Bushaqer¹,

Jama²,

Turki³

2016

BMB

View full text Add to dashboard Cite

Myomectomy as an organ-preserving procedure has become an established alternative to hysterectomy 1-3. An increasing number of women in their fourth to fifth decade request conservative surgery to preserve their reproductive potential 2,3. New advances in assisted reproductive techniques permit women in later reproductive years to bear a child if the uterus is still intact. Submucous and intramural myoma decreases fertility and its removal is beneficial and necessary when the myoma is

show abstract

Pituitrin Injection before Hysteroscopic Curettage for Treating Type I Cesarean Scar Pregnancy in Comparison with Uterine Artery Embolization: A Retrospective Study

Rahman

Qiu

Yuan

et al. 2022

J Obstet Gynecol India

View full text Add to dashboard Cite

Assessment of Blood Loss in Abdominal Myomectomy by Intramyometrial Vasopressin Administration Versus Conventional Tourniquet Application

Cited by 16 publications

References 14 publications

A comparative study between the efficacy of local intra-myometrial injection of vasopressin and octreotide acetate, in reducing blood loss during myomectomy

A comparative study between the efficacy of local intra-myometrial injection of vasopressin and octreotide acetate, in reducing blood loss during myomectomy

Intra and Postoperative Morbidity Associated with Myomectomy

Pituitrin Injection before Hysteroscopic Curettage for Treating Type I Cesarean Scar Pregnancy in Comparison with Uterine Artery Embolization: A Retrospective Study

Contact Info

Product

Resources

About