Assessment of biventricular function with speckle tracking echocardiography in newly-diagnosed adult-onset asthma

Baysal, Sadettin Selçuk; Has, Mehmet

doi:10.1080/02770903.2020.1847928

Cited by 7 publications

(1 citation statement)

References 29 publications

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“…In this study, the strain parameters for the RV were obtained on the apical RV focused view, which was relatively feasible and repeatable. Previous studies have shown that STE-derived strain parameters could be successfully used to evaluate the long axis function of RV in various clinical circumstances [ 7 ]. Of note, for patients with PH, the level of pulmonary artery pressure may not fully reflect the severity of RV dysfunction as well as the efficacy of associated treatment.…”

Section: Discussionmentioning

confidence: 99%

Measuring of strain parameters reflects changes of right ventricular function before and after thrombolytic therapy in patients with acute pulmonary embolism

Zhang

Shen

et al. 2022

Int J Cardiovasc Imaging

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Strain parameters on speckle tracking echocardiography (STE) have been proposed as effective indexes for evaluating right ventricular (RV) function. This pilot study investigated the role of STE-derived strain parameters in assessing global and regional RV myocardial mechanical changes in patients with acute pulmonary embolism (PE) before and after thrombolytic therapy. In this case–control study, a total of 73 PE patients, 34 with pulmonary hypertension (PH) and 39 without PH, who underwent thrombolytic therapy were included. Healthy volunteers were included as controls. The peak longitudinal systolic strain (PLSS) and time to PLSS (TTP) for the global and regional RV were analyzed by STE software immediately before and 14 days after thrombolytic therapy. Changes in STE-derived strain parameters and conventional ultrasound parameters were compared. PLSS and TTP decreased before treatment in PE patients compared with measurements in the control group, particularly in those with PH. Also, the strain parameters decreased more significantly for the free wall than for the septum wall (P < 0.05). Moreover, the RV diastolic diameter (RVDD) and RV/left ventricular (LV) diameter ratio increased, while RV fraction shortening (RVFS), RV fractional area change (RVFAC), tricuspid regurgitation pressure gradient (TRPG), and tricuspid annular peak systolic excursion (TAPSE) decreased (P < 0.05). The global strain parameters for the RV were positively correlated with RVDD and RV/LV diameter ratio, but negatively correlated with RVFS, RVFAC, TRPG, and TAPSE (P < 0.05). After treatment, the strain parameters differed significantly between PE patients with PH and controls but did not differ between PE patients without PH and controls. STE-derived parameters are effective for detecting changes in global and regional RV function in PE patients with or without acute PH.

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Section: Discussionmentioning

confidence: 99%