Assessment of Atrial Electromechanical Delay and Left Atrial Mechanical Functions in Patients with Ulcerative Colitis

Nar, Gökay; Ergül, Bilal; Aksan, Gökhan; İnci, Sinan

doi:10.1111/echo.13213

Cited by 19 publications

(35 citation statements)

References 31 publications

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“…AEMD was measured from the beginning of the electrocardiogram P-wave to the initial point of the spectral TDI-derived A' as described previously [9][10][11][12]. In this study, AEMD was obtained for the septal (septal EMD) and lateral (lateral EMD) sides of the mitral annulus.…”

Section: Measurement Of Aemdmentioning

confidence: 99%

“…Another reason for the relatively prolonged AEMD in PAF patients may be related to an effect of inflammatory cytokines [21]. Systemic inflammation reportedly causes subclinical cardiac damage even in an early phase of atherosclerosis [22], which may be linked to the AEMD prolongation observed in patients with diabetes mellitus, ulcerative colitis, and those with psoriasis [9][10][11].…”

Section: Previous Studies On Aemd and Afmentioning

confidence: 99%

“…An increased left atrial (LA) volume index is also known as a strong predictor of AF [3][4][5]. It has been reported that the intra-and interatrial conduction time, that is, the atrial electromechanical delay (AEMD), is an index of reflecting pathological changes of the atria [6][7][8][9][10][11][12][13]. AEMD can be measured not only by invasive electrophysiologic study but also by echocardiographic tissue Doppler imaging (TDI) [7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, AEMD was shown to be prolonged in various conditions other than cardiac disorders such as diabetes mellitus and ulcerative colitis [9][10][11][12]. However, most of the previous studies regarding AEMD were performed based on the comparison between patients in such conditions and normal controls [9][10][11][12]; do not seem to include patients with similar clinical background to AF patients.…”

Section: Introductionmentioning

confidence: 99%

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Usefulness of Tissue Doppler-derived Atrial Electromechanical Delay for Identifying Patients with Paroxysmal Atrial Fibrillation

Akamatsu

Ito

Miyamura

et al. 2020

Preprint

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Background: Tissue Doppler imaging (TDI)-derived atrial electromechanical delay (AEMD), has been reported to be useful for predicting development of atrial fibrillation (AF). However, its usefulness remains unknown when analyzed along with patients seemingly at high-risk for AF as controls. From this standpoint, we investigated whether AEMD would be of use for identifying patients with paroxysmal AF (PAF).Methods: We analyzed TDI recordings to obtain AEMD in 73 PAF patients. Thirty-nine patients with multiple cardiovascular risk factors (MRFs) but without history of AF and 61 healthy individuals served as disease and healthy controls, respectively. AEMD was defined as the time-interval between the electrocardiogram P-wave and the beginning of the spectral TDI-derived A' for the septal (septal EMD) and lateral (lateral EMD) sides of the mitral annulus.Results: There was no significant difference in the left atrial volume index between PAF patients and disease controls (28 ± 5 mL/m2 vs. 27 ± 5 mL/m2). PAF patients had longer AEMD, particularly for the lateral EMD (78 ± 26 ms), compared with disease (62 ± 21 ms, P = 0.003) and healthy (53 ± 24 ms, P <0.001) controls. Multivariate logistic regression analysis revealed that the lateral EMD (OR 1.42, 95%CI 1.16 -1.75, P <0.001), along with the left atrial volume index (OR 2.86, 95%CI 1.70 -4.80, P <0.001), was one of the significant independent associates of identifying PAF patients.Conclusions: According to our data, analyzed along with MRFs patients, AEMD seems to be a useful index of identifying patients at risk for AF.

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Section: Measurement Of Aemdmentioning

confidence: 99%

Section: Previous Studies On Aemd and Afmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Usefulness of Tissue Doppler-derived Atrial Electromechanical Delay for Identifying Patients with Paroxysmal Atrial Fibrillation

Akamatsu

Ito

Miyamura

et al. 2020

Preprint

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“…The risk of AF is increased in patients with rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus and psoriasis, which all implicate systemic inflammation in their pathogenesis [8]. However, the relationship between JIA and AF is not yet obviously understood as in other rheumatic diseases.…”

Section: Introductionmentioning

confidence: 99%

Assessment of left atrial mechanical functions and atrial electromechanical delay in Juvenile idiopathic arthritis by tissue Doppler echocardiography

et al. 2016

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BackgroundJuvenile idiopathic arthritis (JIA) is a systemic chronic inflammatory disease. Studies using tissue Doppler imaging (TDI) for the evaluation of cardiac functions of children with JIA are limited. Thus, this study was conducted to evaluate Left ventricular function, left atrial mechanical functions and atrial electromechanical delay in JIA.MethodsThis study was carried out as a across sectional study. A total of 34 patients with active JIA and 34 controls were included. Atrial electromechanical delay and left atrial (LA) mechanical functions in addition to systolic and diastolic left ventricular (LV) functions were measured by using conventional echocardiography and TDI. Assessment of disease activity was done using Juvenile arthritis disease activity score (JADAS-27).ResultsJIA patients had abnormal atrial electromechanical coupling as established from prolonged lateral mitral annulus (PA lateral), septal mitral annulus (PA septum), inter-atrial and intra-atrial electromechanical delays compared with healthy controls. Left ventricular filling abnormalities were found characterized by a reduced E/A ratio (1.07 ± 0.56 vs. 1.48 ± 0.16, p = 0.01). E/Em was significantly higher in patients with JIA (7.58 ± 1.79 vs. 4.74 ± 1.45, p = 0.003) denoting impaired diastolic function. Left atrial mechanical functions assessment showed significantly decreased LA passive emptying fraction, increased LA active emptying fraction and LA total emptying volume in JIA patients (p = 0.01, p = 0.01, p = 0.03 respectively).ConclusionAtrial electromechanical coupling intervals, and LA mechanical functions were impaired which can be considered as an early form of subclinical cardiac involvement in JIA patients. Significant diastolic functional abnormalities exist in JIA.

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Atrial peak longitudinal strain may be predictive of pancolitis in patients with ulcerative colitis

Kahyaoğlu

Günay

Bayam

et al. 2019

J of Clinical Ultrasound

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BackgroundUlcerative colitis is a chronic idiopathic inflammatory bowel disease of the colon that is characterized by a relapsing and remitting course. Previous studies have shown that arterial stiffness, carotid intima media thickness, atrial electromechanical delay, and global longitudinal strain suggested subclinical cardiovascular disorders in ulcerative colitis patients. The aims of our study was to evaluate the left atrial function of patients with ulcerative colitis by using speckle tracking echocardiography, and to assess the relationship between echocardiographic variables and the extent of the disease.MethodsWe recruited 51 outpatients with ulcerative colitis in remission phase and 52 healthy volunteers. The ulcerative colitis patients were evaluated by for the extent of the disease by endoscopy at the initial diagnosis.Results E/Em, left atrial volume, and left atrial stiffness index were higher, and peak atrial longitudinal strain was lower in pancolitis than in non‐pancolitis patients. In the multivariate logistic regression test, peak atrial longitudinal strain and E/Em were found to be independent predictors for pancolitis.ConclusionEarly detection of myocardial abnormalities by conventional echocardiography and speckle tracking echocardiography, which is a simple and non‐invasive technique, may be useful for giving insights to the extent of the disease in ulcerative colitis patients.

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Assessment of Atrial Electromechanical Delay and Left Atrial Mechanical Functions in Patients with Ulcerative Colitis

Abstract: The current study reported that LA volume and mechanical functions degenerated and AEMD increased in patients with UC when compared to the control group. These findings demonstrate that UC may have effects on LA electromechanical functions related to duration of disease.

Cited by 19 publications

References 31 publications

Usefulness of Tissue Doppler-derived Atrial Electromechanical Delay for Identifying Patients with Paroxysmal Atrial Fibrillation

Usefulness of Tissue Doppler-derived Atrial Electromechanical Delay for Identifying Patients with Paroxysmal Atrial Fibrillation

Assessment of left atrial mechanical functions and atrial electromechanical delay in Juvenile idiopathic arthritis by tissue Doppler echocardiography

Atrial peak longitudinal strain may be predictive of pancolitis in patients with ulcerative colitis

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