Assessment of Antimicrobial Activity of Moringa Oleifera and Azadirachta Indica Leaves Against Enterococcus Faecalis, Candida Albicans - An Invitro Study.

Shetty, B. V.

doi:10.21474/ijar01/9418

Cited by 2 publications

(2 citation statements)

References 6 publications

(6 reference statements)

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“…Numerous studies showed that OCT has a potent antimicrobial effect against E. faecalis [ 16 , 17 ]. In this study, M. oleifera plant was chosen as it has a wide range of antimicrobial properties which have been investigated by some studies, which examined different parts of the plant and different methods of preparation of extract [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

A Comparative Evaluation of Antibacterial Efficacy of Moringa oleifera Leaf Extract, Octenidine Dihydrochloride, and Sodium Hypochlorite as Intracanal Irrigants against Enterococcus faecalis: An In Vitro Study

Alharbi

Alqahtani

et al. 2023

International Journal of Dentistry

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Objectives. The aim of this study is to investigate and compare the microbial efficacy of Moringa oleifera leaf extract, octenidine dihydrochloride (OCT), NaOCl, and their combinations as intracanal irrigants against Enterococcus faecalis. Materials and Methods. Sixty single-rooted mandibular premolars were decoronated followed by root canal preparation. Each root specimen was autoclaved, inoculated with E. faecalis, and incubated at 37°C for 48 hr. Then, the specimens were divided into six groups based on the irrigation solution used: 2.5% NaOCl (Group 1), 0.1% OCT (Group 2), M. oleifera leaves extract (Group 3), a combination of M. oleifera extract and 1.25% NaOCl (Group 4), a combination of M. oleifera extract and OCT (Group 5) and normal saline (Group 6). Microbial samples were taken from each root canal before (S1) and after (S2) irrigation and the bacterial viability was assessed using colony-forming units (CFU) on bile esculin agar plates. Results. Comparing the number of CFU/ml before and after irrigation showed a significant reduction ( P < 0.001 ) in all studied groups. Comparison between the CFU/ml after irrigation by NaOCl and each of the combination groups showed a significant difference. Conclusion. M. oleifera leaves extract and 0.1% OCT solutions have antibacterial effect against E. faecalis comparable to 2.5% NaOCl and might be used as root canal irrigants. The combination groups showed better antimicrobial activities than individual irrigants. However, further studies are required to investigate the biocompatibility and possible toxic effects of the tested irrigants.

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Section: Discussionmentioning

confidence: 99%

A Comparative Evaluation of Antibacterial Efficacy of Moringa oleifera Leaf Extract, Octenidine Dihydrochloride, and Sodium Hypochlorite as Intracanal Irrigants against Enterococcus faecalis: An In Vitro Study

Alharbi

Alqahtani

et al. 2023

International Journal of Dentistry

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“…According to a study conducted by Shetty et al (2019), Moringa oleifera and Azadirachta indica demonstrated an antibacterial effect against Enterococcus faecalis. They concluded that these natural products could be used effectively as antimicrobial agent in root canal therapy.…”

Section: Discussionmentioning

confidence: 99%

A novel plant based intra canal medicament: ease of removal and effect on radicular dentine microhardness

et al. 2021

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Background This study aimed to evaluate the remaining amount of intra canal medicament in the root canals and their effect on microhardness of radicular dentine. In this study, ninety straight single-rooted teeth were used. Teeth were decoronated at the cemento-enamel junction to ensure a uniform root length of 14 mm (± 1 mm). Root canals were prepared using ProTaper rotary files till size F5. The teeth were then randomly assigned to 3 treatment groups (n = 30); Group 1: Ca(OH)2 pastes (Metapex), Group 2: Moringa oleifera leaf powder mixed with Moringa oleifera extract liquid and Group 3: Moringa oleifera root powder mixed with Moringa oleifera extract liquid. The access openings of all teeth were sealed with Cavit and all teeth were kept in the incubator at 37 °C and 100% humidity for 1 week. After 1 week, the intra canal medicament paste was removed from all teeth. For examination of the ease of removal of the intracanal medicaments, root canals were sectioned longitudinally into buccal and lingual halves and were examined under stereomicroscope at 25× magnification. The remaining amount of intracanal medicaments was calculated using image analysis software (Image j). For microhardness evaluation, forty-five specimens were longitudinally sectioned in a bucco-lingual direction then the roots were split. The root segments were then horizontally embedded in autopolymerizing acrylic resin leaving their dentin surface exposed. The dentin surface of the mounted specimens was ground flat and smooth and polished to obtain a smooth surface. Microhardness measurement was recorded for each sample at baseline before and after application of the three intracanal medications using Vickers Microhardness Tester at magnification of 100× using a 25 g load for 10 s. Results Regarding the evaluation of the ease of removal of the intracanal medicaments after irrigation: apically, the Ca(OH)2 recorded the highest mean value of the residual remnants with a statistically significant difference with both Moringa oleifera leaf and root. The microhardness evaluation results showed that all groups showed increase in the microhardness after application of the intracanal medicament for 1 week with no statistically significant difference between them. Conclusions Moringa oleifera could be removed easily from the root canals and showed increase in the microhardness of root canal dentin similar to the commonly used calcium hydroxide.

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Assessment of Antimicrobial Activity of Moringa Oleifera and Azadirachta Indica Leaves Against Enterococcus Faecalis, Candida Albicans - An Invitro Study.

Cited by 2 publications

References 6 publications

A Comparative Evaluation of Antibacterial Efficacy of Moringa oleifera Leaf Extract, Octenidine Dihydrochloride, and Sodium Hypochlorite as Intracanal Irrigants against Enterococcus faecalis: An In Vitro Study

A Comparative Evaluation of Antibacterial Efficacy of Moringa oleifera Leaf Extract, Octenidine Dihydrochloride, and Sodium Hypochlorite as Intracanal Irrigants against Enterococcus faecalis: An In Vitro Study

A novel plant based intra canal medicament: ease of removal and effect on radicular dentine microhardness

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