Assessment of antibiotic prescribing pattern in pediatric patients: A cross-sectional hospital-based survey

Pradeepkumar, Bhupalam; Alameri, Tawfeek; Narayana, G; Reddy, Y. Padmanabha; Jinka, Dasaratha Ramaiah

doi:10.4103/cjhr.cjhr_52_17

Cited by 20 publications

(39 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…System of illness was another factor that was found to be associated with the use of antibiotics, with respiratory and gastro-intestinal conditions mostly resulting in antibiotic prescriptions. The findings confirmed what other researches have reported that most of the respiratory and gastro-intestinal conditions are treated with antibiotics despite the absence of confirmatory tests to indicate bacterial cause [20,23]. Despite most of the conditions being appropriate for antibiotic treatment, several cases did not require antibiotic treatment and the highest value was found in infectious diseases.…”

Section: Discussionsupporting

confidence: 89%

“…From this study, it was found that the majority of paediatric patients affected by irrational antibiotic usage were those within the age group of 1 month to 5 years. This is similar to the findings in Guyana, Germany, and India [5,19,20]. This age group is prone to different diseases especially conditions of the respiratory and gastro-intestinal systems due to their immature and yet developing immune system [19][20][21].…”

Section: Discussionsupporting

confidence: 88%

“…This is similar to the findings in Guyana, Germany, and India [5,19,20]. This age group is prone to different diseases especially conditions of the respiratory and gastro-intestinal systems due to their immature and yet developing immune system [19][20][21]. In India, it was found that the majority of the paediatric patients that received antibiotics were from the age of 5-12 years [22].…”

Section: Discussionsupporting

confidence: 86%

See 2 more Smart Citations

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Mudenda¹

2020

Int J Pharm Pharmacol

View full text Add to dashboard Cite

The use of antimicrobial agents has become a routine practice for the treatment of paediatric illnesses. The uncontrolled use of antibiotics has caused a rise in antimicrobial resistance. This study aimed to assess the antibiotic prescribing patterns in paediatric patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia. This was a cross-sectional study conducted between April 2019 to July 2019. The study population included both in-patients and outpatients aged between one month and eighteen years whose medical files were reviewed. A sample size of 357 medical files was conveniently sampled. Statistical Package for Social Sciences version 21.0 was used for data analysis. A chi-square test was used to assess the association between categorical variables. A p<0.05 was considered to be statistically significant at 95% confidence level. The majority of the medical files 230 (64.4%) were for paediatrics in the age group of 1 month to 5 years. Antibiotic prescribing was found to be 78.7%. The study revealed that 119 (33.3%) of patients required antibiotics and were on antibiotic treatment while 46 (12.9%) did not require antibiotics but were on antibiotic treatment. The most common diseases 147 (41.2%) were those affecting the respiratory system. The most commonly prescribed antibiotics were penicillins 154 (54.8%), followed by cephalosporins 88 (31.3%). The association between age, white blood cell count status, and system of illness with antibiotic use were statistically significant (χ 2 =15.083, p=0.001; χ 2 = 6.571, p=0.037 and χ 2 =27.717, p<0.0001). The study also found that the frequency of antibiotic use was high among paediatric patients as per the World Health Organization's prescribing indicators. The most commonly prescribed antibiotics to paediatric patients were penicillins.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 86%

See 1 more Smart Citation

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Mudenda¹

2020

Int J Pharm Pharmacol

View full text Add to dashboard Cite

show abstract

“…Generic prescription rate was found to be more than that of study conducted in Andhra Pradesh, India (23.43%) and in North East India (8.2%) but less than similar type of study conducted in Punjab, India (58%), Sudan (49.3%) and Nigeria (68.9%). 6,[15][16][17][18] Generic prescribing has been found to reduce the cost of medicines and also promote better communication among health care providers. This study found that oral route (56%) of administration was common than parenteral route (44%) which is contrast to the study published by Palikhe N et al (75% parenteral, 25% oral), Kanish et al (92% parenteral, 8% oral), Dutta et al (75% parenteral) and Laya VR et al (87.7% parenteral, 12.3% oral).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Prescription Pattern of Antimicrobial Agents in Hospitalised Paediatric Patients in a Tertiary Care Hospital of Kathmandu, Nepal

Khadka

Rayamajhi

Shrestha

2018

J. Nepal Paedtr. Soc.

View full text Add to dashboard Cite

Introduction: Infectious diseases are one of the most frequent reasons for hospital admission for children and antimicrobials are commonly used to treat them. There is higher prevalence of irrational prescriptions of antimicrobials in such population. This study was conducted to survey the pattern of antimicrobial prescription in Paediatric inpatient. Material and Methods: This was retrospective, descriptive, observational study. The data was collected from prescription records. The paediatric population included in the study was categorised into three age groups. A total of 87 prescriptions were studied and the information was recorded in performa. Data were recorded in MS Excel and Graph Pad Prism version 6 was used for analysis. Results: The number of male child was outnumbered by female child. The average age of the patient on antimicrobial prescription was 5.34 ± 2.18 years. The mean duration of hospital stay was 6.17 ± 2.01 days. The common indications for antimicrobial prescriptions were upper respiratory tract infections, diarrhoeal illness, urinary tract infections, enteric fever, etc. The antimicrobials prescription rate was 1.33. Oral route was found to be commonly used than parenteral route. The generic prescription rate was 33.6%. The most common drug prescribed was ceftriaxone followed by amoxicillin + clavulanic acid, ciprofloxacin, metronidazole and amikacin. The 62.5% of antimicrobials were prescribed from National Essential List of Medicines. Conclusion: This study highlights the prescription pattern of antimicrobial agents in hospitalised Paediatric population in a tertiary care hospital.

show abstract

“…Bacterial resistance is a risk for both community and individual which leads to fatal outcomes due to resistant for certain bacterial strains [2]. Inappropriate use of antibiotics results in antimicrobial resistance which leads to high risk in morbidity, mortality, and economic crisis on health care service [3]. In recent times, physicians are including antibiotics as an empirical therapy which may or may not be rational [4,5].…”

Section: Introductionmentioning

confidence: 99%

An Evaluation on Prescribing Pattern of Antibiotics in Paediatric Inpatients at Tertiary Care Hospital

Sabishruthi¹,

Kavitha²,

B³

et al. 2019

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Our objective of the study was to evaluate the prescribing patterns of drugs with cost analysis in pediatric inpatients at tertiary care hospital. Methods: It is an observational prospective study carried out in pediatric inpatients with a sample of 180 patients based on age, inclusion, and exclusion criteria for period of 3 months. The patient’s data were collected using patient case record form and analysis of the data was done. Results: Of 180 patients data were collected, the results show that majority of gender admitted in the hospital were male children 94 (52%) and many are from age group of early childhood (2–5 years) 67 (37%). Respiratory tract infections are diagnosis most commonly analyzed and off overall 236 prescribed antibiotics cephalosporins 86 (43%) and combination of amoxicillin + clavulanic acid 25 (71%) is the class of antibiotics prescribed higher than other class of drugs. Parental 173 (73%) route of administration was observed to be followed more than other route. The percentage of cost variation of antibiotics observed in the study reveals that the huge variations were seen in the cost of medication in maximum and minimum cost. Conclusion: The present study reveals that the prescribed antibiotics were as per the diagnosis of the patient and not by proceeding proper culture sensitivity testing. Hence, awareness about antibiotic must be created among practicing physicians to increase the therapeutic compliance of the patient.

show abstract

Assessment of antibiotic prescribing pattern in pediatric patients: A cross-sectional hospital-based survey

Cited by 20 publications

References 0 publications

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Evaluation of the Prescription Pattern of Antimicrobial Agents in Hospitalised Paediatric Patients in a Tertiary Care Hospital of Kathmandu, Nepal

An Evaluation on Prescribing Pattern of Antibiotics in Paediatric Inpatients at Tertiary Care Hospital

Contact Info

Product

Resources

About