Assessment of Antibacterial, Cytotoxicity and Wound Healing Influence of Copper Nanoparticles Synthesized using Probiotic Bacteria

Abstract

The present article targeted to biosynthesis and description of copper oxide nanoparticles (CuO NPs) using probiotic isolate and assessment the antibacterial, cytotoxicity of these NPs and its effect on wound heals. The CuO NPs are biosynthesized using probiotic isolate identified as Bacillus cereus. These CuO NPs are characterized using UV, FT-IR, Zeta and TEM. The antibacterial efficiency is assayed by agar plate diffusion protocol. Results assured that the CuO NPs can prevent Staphylococcus aureus jointly Escherichia coli growth. MTT procedure exercised to detect cytotoxicity and wound healing effects. The results revealed that CuO NPs can use as antibacterial agent with non-significant effects on host cells and wound healing.