Assessment of Anti-Carcinogenic Potential of Neem (<i>Azadirachta indica</i>) Leaf Extract Loaded Calcium Phosphate Nanoparticles against Experimentally Induced Mammary Carcinogenesis in Rats
S. G. Chavhan,
C. Balachandran,
A. P. Nambi
et al.
Abstract:Considering the need for alternative medicine in alleviation of tumors and use of nanotechnology in furthering the action of herbal/natural products, the present study was designed to evaluate the anti-carcinogenic potential of Neem leaf Extract (NE) loaded calcium phosphate nanoparticles (NE-CaNP) on 7, 12-Dimethylbenzanthracene (DMBA) induced mammary tumors in female Sprague-Dawley rats. Ultrastructurally, the NE-CaNP were smooth, spherical with a tendency to agglomerate and evenly distributed. The NE-CaNP h… Show more
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