Assessment of Air Cavities in High-Dose-Rate Vaginal Cuff Brachytherapy Using Cylindrical and Balloon-Type Applicators

Abstract

Conclusion: Distant failure still remains the overwhelming challenge for patients with UPSC. Our observations suggest that better local regional control with no detriment in DM, DFS, and OS is achieved using CCRT compared to SCRT schedule. CCRT addresses both local/regional and systemic disease upfront. Delaying RT until completion of systemic therapy may compromise local/pelvic control. Further, study with larger number of pts and longer follow-up is needed to define the optimal sequencing of combined modality therapy in UPSC.