Assessment of acute bowel function after radiotherapy for prostate cancer: Is it accurate enough?

Bonet, Marta; Cayetano, L.; Nuñez, M.; Jovell-Fernández, Esther; Aguilar, Alfredo; Ribas, Yolanda

doi:10.1007/s12094-017-1749-4

Cited by 5 publications

(2 citation statements)

References 31 publications

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“…Side effects from chemotherapy may have contributed to some of the late symptoms, and this should be taken into consideration when interpreting the results. The importance of screening for pre-existing bowel symptoms in order to adequately evaluate radiotherapy-induced bowel symptoms has been highlighted [39]. We observed that higher levels of bowel symptoms at baseline were associated with more symptoms during both the acute and the late phases for the majority of symptoms.…”

Section: Discussionmentioning

confidence: 75%

Effects of a nutrition intervention on acute and late bowel symptoms and health-related quality of life up to 24 months post radiotherapy in patients with prostate cancer: a multicentre randomised controlled trial

Forslund

Ottenblad

Ginman

et al. 2019

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Purpose Radiotherapy to the prostate gland and pelvic lymph nodes may cause acute and late bowel symptoms and diminish quality of life. The aim was to study the effects of a nutrition intervention on bowel symptoms and health-related quality of life, compared with standard care. Methods Patients were randomised to a nutrition intervention (n = 92) aiming to replace insoluble fibres with soluble and reduce intake of lactose, or a standard care group (n = 88) who were recommended to maintain their habitual diet. Bowel symptoms, health-related quality of life and intake of fibre and lactose-containing foods were assessed up to 24 months after radiotherapy completion. Multiple linear regression was used to analyse the effects of the nutrition intervention on bowel symptoms during the acute (up to 2 months post radiotherapy) and the late (7 to 24 months post radiotherapy) phase. Results Most symptoms and functioning worsened during the acute phase, and improved during the late phase in both the intervention and standard care groups. The nutrition intervention was associated with less blood in stools (p = 0.047), flatulence (p = 0.014) and increased loss of appetite (p = 0.018) during the acute phase, and more bloated abdomen in the late phase (p = 0.029). However, these associations were clinically trivial or small. Conclusions The effect of the nutrition intervention related to dietary fibre and lactose on bowel symptoms from pelvic RT was small and inconclusive, although some minor and transient improvements were observed. The results do not support routine nutrition intervention of this type to reduce adverse effects from pelvic radiotherapy.

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Section: Discussionmentioning

confidence: 75%

Effects of a nutrition intervention on acute and late bowel symptoms and health-related quality of life up to 24 months post radiotherapy in patients with prostate cancer: a multicentre randomised controlled trial

Forslund

Ottenblad

Ginman

et al. 2019

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“…The great variation of tools to assess bowel function and the use of non-validated questionnaires complicate the assessment of prevalence of bowel dysfunctions after gynaecological cancer treatment. This was the conclusion of a previous study of our group assessing bowel symptoms after prostate cancer treatment in which defecatory urgency remained undetected after radiotherapy treatment [33]. It should be noted that questionnaires frequently used, such as those from the EORTC, do not fully assess the bowel function.…”

Section: Discussionmentioning

confidence: 75%

Bowel dysfunction in survivors of gynaecologic malignancies

Ribas

Bonet

Torres

et al. 2020

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Purpose To assess the prevalence of bowel dysfunctions after treatment for gynaecological cancer and the impact on the quality of life. Methods We identified a cohort of 217 eligible women treated with radiotherapy (RT) with curative intention, alone or as combined treatment, for gynaecological malignancies at three institutions in Catalonia (Spain). Demographic, diagnosis and treatment modality were reviewed. Patients were sent validated questionnaires to assess bowel function and a set of questions asking on the changes after RT in bowel function, urinary function, sexuality, pain and lymphoedema. Results Questionnaires were returned by 109 patients (50.2%) with a mean age of 65 ± 11 years. Of them, 71.8% had been treated for endometrial cancer and 28.2% for cervical cancer. Overall, 42.7% of patients reported bowel dysfunction, affecting their quality of life in 36% of cases. Symptoms were more frequent in patients who had undergone external beam RT compared to brachytherapy. The most common symptom was defecatory urgency which was reported by more than 40% of patients according to the St Mark's score, although it was less common in other questionnaires. Overall, faecal incontinence ranged between 10 and 15%, and usual loose stools and diarrhoea were reported by 13.5% and 5.1%, respectively. Conclusion Prevalence of bowel symptoms after treatment of gynaecological malignancies is high. A systematic evaluation using validated questionnaires should be performed in order to allow the decision-making process and also because there are a number of treatments available to improve the quality of life of cancer survivors.

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Virtual Imaging for Patient Information on Radiotherapy Planning and Delivery for Prostate Cancer

Martínez-Albaladejo

Sulé-Suso

Lines³

et al. 2021

Medical Image Understanding and Analysis

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Assessment of acute bowel function after radiotherapy for prostate cancer: Is it accurate enough?

Abstract: Bowel symptoms such as urgency may remain undetected by usual tools to assess toxicity after radiotherapy. Assessment of bowel toxicity should be reappraised in order to identify those patients who may have symptoms with an impact on their quality of life.

Cited by 5 publications

References 31 publications

Effects of a nutrition intervention on acute and late bowel symptoms and health-related quality of life up to 24 months post radiotherapy in patients with prostate cancer: a multicentre randomised controlled trial

Effects of a nutrition intervention on acute and late bowel symptoms and health-related quality of life up to 24 months post radiotherapy in patients with prostate cancer: a multicentre randomised controlled trial

Bowel dysfunction in survivors of gynaecologic malignancies

Virtual Imaging for Patient Information on Radiotherapy Planning and Delivery for Prostate Cancer

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