Assessment of acaricidal activity of nanoscale ZnO encapsulated piperine formulation against
            <i>Rhipicephalus microplus</i>

Kancharana, Snigdha; Chengalva, Rayulu Vukka; Kothapalli, Srinivasa Rao; Yegireddy, Muralidhar; Bollini, Sreedevi; Vara, Prasad Tollamadugu Naga Venkata Krishna

doi:10.1049/iet-nbt.2020.0159

Cited by 4 publications

(2 citation statements)

References 44 publications

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“…Nano-biotechnology is considered a novel approach in the treatment of arthropod vectors and parasitic infections [ 18 ]. Synthesized ZnO NPs have been proven to have acaricidal activity against Rhipicephalus (Boophilus) microplus [ 19 – 21 ], in addition to pediculocidal activity against Pediculus humanus capitis (Phthiraptera: Pediculidae) and larvicidal activity against mosquitoes [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Acaricidal Efficacy of Biosynthesized Zinc Oxide Nanoparticles Against Hyalomma dromedarii (Acari: Ixodidae) and Their Toxic Effects on Swiss Albino Mice

et al. 2022

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Purpose The current study aimed to investigate the efficacy of zinc oxide nanoparticles (ZnO NPs) synthesized by Melia azedarach aqueous extract to control Hyalomma dromedarii tick, and to evaluate their toxic effects on Swiss albino mice. Methods ZnO NPs were synthesized using M. azedarach aqueous extract. UV–visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive spectroscopy were used to characterize the synthesized NPs. Egg, nymph, larva, and adult immersion tests were used for bioassay of tick stages with the synthesized ZnO NP. A toxicity study was performed on Swiss albino mice after treatment with 1/10 of the oral LD50 of ZnO NPs (8437 mg/kg) for 5 successive days by oral gavage. Results The LC50 of ZnO NPs on the eggs, larvae, and nymphs was 11.6, 8.03, and 3.9 mg/ml, respectively. The reproductive performance of females treated with ZnO NPs was lower than that of untreated females. The hematological results showed an insignificant increase in the level of white blood cells with normal red blood cells, hemoglobin, in addition to normal platelet count. The biochemical analysis showed an insignificant increased level (P > 0.05) of alkaline phosphatase and alanine aminotransferase. The liver and kidney suffered few histopathological changes after oral administration of ZnO NPs. Conclusion These results suggest that ZnO NPs have good acaricidal activity against eggs, larvae, and engorged nymphs of H. dromedarii. ZnO NPs minimized the number of eggs laid by engorged females and the hatchability of their eggs. ZnO NPs did not affect unfed adults. The toxicity results of the mice revealed insignificant changes in the hemogram, biochemistry, with liver and kidney suffering few histopathological changes. Future studies are needed to assess application routes (topical vs oral). Based on these findings, ZnO NPs may be incorporated in the control of camel tick H. dromedarii.

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Section: Introductionmentioning

confidence: 99%

Acaricidal Efficacy of Biosynthesized Zinc Oxide Nanoparticles Against Hyalomma dromedarii (Acari: Ixodidae) and Their Toxic Effects on Swiss Albino Mice

et al. 2022

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“…Disorder in the synthesis of vitellogenin leads to a reduction in the number of eggs and egg masses and, subsequently, the development of eggs. Moreover, Kirthi et al (2011) and Kancharana et al (2020) confirmed that the significant inhibition of the egg‐laying ability indicates a disruption in the mechanisms implicated in oviposition. Another assumption that explains the reduction of egg‐laying capacity is the degeneration of the hermaphrodite gland (El‐Hommossany & El‐Sherbibni, 2011).…”

Section: Discussionmentioning

confidence: 92%

Reproductive performance of freshwater snail, Helisoma duryi under the effect of bulk and nano zinc oxide

Kandeil,

Salem,

Eissa

et al. 2024

J Exp Zool Pt A

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Nanotechnology has been used to apply nanoparticle essential elements to enhance the ability of animals to absorb these elements and consequently improve their reproductive performance. High concentrations of nanoparticles (NPs) can directly harm a range of aquatic life forms, ultimately contributing to a decline in biodiversity. Helisoma duryi snails are a good model for studying the toxicological effects of bulk zinc oxide (ZnO‐BPs) and nano zinc oxide (ZnO‐NPs) on freshwater gastropods. This study aimed to compare the toxic effects of ZnO‐BPs and ZnO‐NPs on H. duryi snails and explore how waterborne and dietary exposure influenced the reproductive performance of this snail. ZnO‐BPs and ZnO‐NPs were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X‐ray powder (XRD). This study revealed that the size of ZnO‐BPs and ZnO‐NPs were 154 nm and 11–31 nm, respectively. The results showed that exposure of adult snails to sub‐lethal concentrations of both ZnO forms (bulk and nano) for 24 h/week for 4 weeks markedly changed their reproductive performance in a concentration‐dependent manner, where fecundity was negatively affected by high concentrations. It was concluded that dietary exposure to the lowest tested concentration of ZnO‐NPs (1 ppm) has a positive effect as the number of eggs and egg masses/snails increased and the incubation period decreased. Also, poly‐vitelline eggs (The formation of twins) were observed. ZnO‐NPs at low concentrations positively affect the reproductive performance of snails, especially after dietary exposure. The results revealed that 1 ppm ZnO‐NPs could be supplementary provided to snails to improve their fertility, reduce the developmental time course, increase hatchability percentage, and produce poly‐vitelline eggs.

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Insecticidal activity of metallic nanopesticides synthesized from natural resources: A review

Han

Gao

et al. 2022

Environ Chem Lett

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Assessment of acaricidal activity of nanoscale ZnO encapsulated piperine formulation against Rhipicephalus microplus

Cited by 4 publications

References 44 publications

Acaricidal Efficacy of Biosynthesized Zinc Oxide Nanoparticles Against Hyalomma dromedarii (Acari: Ixodidae) and Their Toxic Effects on Swiss Albino Mice

Acaricidal Efficacy of Biosynthesized Zinc Oxide Nanoparticles Against Hyalomma dromedarii (Acari: Ixodidae) and Their Toxic Effects on Swiss Albino Mice

Reproductive performance of freshwater snail, Helisoma duryi under the effect of bulk and nano zinc oxide

Insecticidal activity of metallic nanopesticides synthesized from natural resources: A review

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