Assessment of a novel genetic counselling intervention to inform assisted reproductive technology treatments and other family-building options in adults with cystic fibrosis

Kushary, Sulagna; Ali, Nadia; Spencer, Jessica B.; Dokson, Jamie; Hunt, William R.

doi:10.1016/j.rbms.2021.05.001

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…Providing emotional support and facilitating connections to additional family building, obstetric, and postnatal resources complements and enhances the role of the other members of the care team [28]. Genetic counseling can improve patient knowledge and facilitate decision-making about familybuilding options [29].…”

Section: Genetic Counselingmentioning

confidence: 99%

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Reproductive Counseling and Care in Cystic Fibrosis: A Multidisciplinary Approach for a New Therapeutic Era

McGlynn

DeCelie-Germana

Kier

et al. 2023

Life

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With the advent of highly effective modulator therapies, many people with cystic fibrosis (CF) are living longer, healthier lives. Pregnancy rates for women with CF more than doubled between 2019 and 2021, reflecting increases in both planned and unplanned pregnancies. For men with CF, CF-associated infertility can be mitigated with assistive reproductive technology, yet patient knowledge of these challenges and options is variable. Preconception and prenatal counseling for individuals with CF and for parents of children with CF who wish to expand their families requires nuanced discussions to promote informed reproductive decisions, drawing from a combination of standard practice recommendations and CF-specific assessments. This review article synthesizes the current literature and practice recommendations regarding reproductive counseling and care in CF, outlining the role of genetic counseling, carrier screening, teratogen counseling, in vitro fertilization and pre-implantation genetic diagnosis, and careful assessment and management of cystic fibrosis-related diabetes when present. Via a multidisciplinary, patient-centered approach, clinicians can support adults with CF and parents of children with CF as they make informed reproductive decisions and embark on family planning.

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Section: Genetic Counselingmentioning

confidence: 99%

“…The cost of some of these approaches can be prohibitive. Learning about the range of options for family building can facilitate decision-making, with or without changing a planned course of action [29].…”

Section: Prenatal Screening and Diagnostic Optionsmentioning

confidence: 99%

Reproductive Counseling and Care in Cystic Fibrosis: A Multidisciplinary Approach for a New Therapeutic Era

McGlynn

DeCelie-Germana

Kier

et al. 2023

Life

View full text Add to dashboard Cite

show abstract

Sexual and Reproductive Health Among Men With Cystic Fibrosis

Campbell,

Zarli,

Schuppe

et al. 2023

Urology

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Features of pubertal development of adolescent girls with cystic fibrosis

Goryainova

Karachentsova

Sibirskaya

et al. 2022

RPJ

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This review is devoted to an urgent and insufficiently studied problem - the characteristics of the pubertal development of girls with cystic fibrosis (CF), the deviations in the period of menarche, the stages of the puberty, anatomical and physiological features of the female reproductive system in this monogenic disease. The increase in life expectancy, as well as the spread and increasing availability of targeted therapies, highlight the need for further research on this topic. Early diagnosis of disorders of pubertal development due to timely prescribed therapy (hormonal) allows not only correcting the timing of the onset of menarche in CF adolescent girls, but also increasing the chances of conceiving and bearing a child.

show abstract

Assessment of a novel genetic counselling intervention to inform assisted reproductive technology treatments and other family-building options in adults with cystic fibrosis

Cited by 3 publications

References 18 publications

Reproductive Counseling and Care in Cystic Fibrosis: A Multidisciplinary Approach for a New Therapeutic Era

Reproductive Counseling and Care in Cystic Fibrosis: A Multidisciplinary Approach for a New Therapeutic Era

Sexual and Reproductive Health Among Men With Cystic Fibrosis

Features of pubertal development of adolescent girls with cystic fibrosis

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