Assessing the Utility of a Prognostication Model to Predict 1-Year Mortality in Patients Receiving Radiation Therapy for Spinal Metastases

Abstract

with both groups, but most notably in the RT group (11.3% vs. 42.4%). RT was associated with inferior 1-year OS on unadjusted modeling (HR Z 1.99, 95% CI Z 1.65-2.38, P < 0.001), with ventilation status and pre-ICU disposition adjusting this finding towards the null on multivariable modeling (HR Z 1.17, 95% CI Z 0.97-1.40, P Z 0.095). Conclusion: Lung cancer patients in the ICU have a poor OS. Although the use of RT in this setting is rare, geographic disparities exist in its utilization in a publically funded healthcare system. Those receiving RT are more likely to present via transfer or the ER, with a significant proportion achieving discharge and a minority prolonged survival, suggesting that RT use may not be futile.