This article considers the implications of a post-liberal order for the international responsibility to protect. It focuses on two questions. First, what challenges will the international responsibility to protect face in a post-liberal order? Second, in light of these challenges, how would the requirements of the international responsibility to protect differ in the post-liberal order? In response to the first question, the article argues that in a post-liberal order the international responsibility to protect is likely to be subject to the “Influence Challenge,” whereby its ability to constrain and influence states decreases. In response to the second question, it argues that the requirements of the international responsibility to protect would be affected in several ways, including necessitating greater consideration of questions of prioritization and requiring a re-evaluation, and potential abandonment, of the currently predominant approach to the responsibility to protect.