Assessing the Relation Between Musculoskeletal Disease Prevalence and Physically Demanding Work

Zaitseva, Nina; Шур, П.З.; Kostarev, Vitaly; Klimenko, A.I.

doi:10.1289/isee.2011.01014

ISEE Conference Abstracts

2011

DOI: 10.1289/isee.2011.01014

|View full text |Cite

Assessing the Relation Between Musculoskeletal Disease Prevalence and Physically Demanding Work

Nina Zaitseva¹,

П.З. Шур²,

Vitaly Kostarev³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2018

2022

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They include noise, heating microclimate, industrial dusts, flammable, explosive and poisonous substances, vibration, ultra-sound, electromagnetic radiation as well as substantial physical loads and work in night shifts [1,[5][6][7]. Domestic studies have confirmed a substantial role that belongs to adverse occupational factors at metallurgic production in developing pathologies of various organs and systems [8,9], including upper respiratory mucosa. They can progress latently and become a factor that induces various respiratory diseases [10].…”

mentioning

confidence: 99%

Assessing index of accumulated cytogenetic disorders in workers employed in metallurgy under exposure to adverse occupaitonal factors

Vlasova¹,

Masyagutova²,

Abdrakhmanova³

et al. 2022

Health Risk Analysis

View full text Add to dashboard Cite

Metallurgy is a major economic branch in Russia with more than 4000 enterprises operating in it and seventy percent of them being city-forming ones. This study focuses on cytological assessment of the oral mucosa and secretion from the middle meatus mucosa in workers employed in metallurgy. The aim of this study was to investigate cytological laboratory indicators in workers employed in metallurgy under exposure to adverse occupational factors. A clinical and diagnostic examination of workers employed at a metallurgical plant in Bashkortostan was performed in 2019–2020; it involved cytological studies of the oral mucosa (buccal epithelium) and the middle meatus mucosa (rhinocytogram). In this study, we applied the Index of cytogenetic disorders accumulation (Iac) that allows for cellular kinetics indicators. The overall hygienic assessment of working conditions for workers employed at the analyzed metallurgic plant corresponds to the hazard category 3.2–3.3 in accordance with the criteria outlined in the Guide R (harmful, class 2 or 3). The research results revealed cytogenetic disorders of buccal epithelial cells in the workers who had contacts with adverse occupational factors. Low likelihood of cytogenetic disorders was established for 66.67 % of the workers; moderate, 9.2 %; high, 23.81 %. We assessed rhinocytograms of the workers exposed to adverse occupational factors and revealed some signs of allergic inflammation characterized with high eosinophil count. The research results confirm high significance of diagnostic procedures for developing an algorithm for screening examinations of working population as well as indicators of health disorders under exposure to adverse occupational factors (noise, heating microclimate, industrial dust, gaseous chemicals).

show abstract

mentioning

confidence: 99%

Assessing index of accumulated cytogenetic disorders in workers employed in metallurgy under exposure to adverse occupaitonal factors

Vlasova¹,

Masyagutova²,

Abdrakhmanova³

et al. 2022

Health Risk Analysis

View full text Add to dashboard Cite

show abstract

Regulation of Organism's Antiviral Immune Response: Mathematical Model, Qualitative Analysis, Results

Трусов¹,

Zaitseva²,

Chigvintsev³

et al. 2018

Math.Biol.Bioinf.

View full text Add to dashboard Cite

To know the processes occurring in the neuroendocrine and immune system, the complex and branching regulation mechanisms should be taken into account. Most of the studies in this area are dedicated to the biological and mathematical description of individual parts of the regulatory mechanisms, and it greatly facilitates the understanding of the phenomena being studied. But there is a lack of comprehensive description of the processes and internal communications. In the present article, a mathematical model for describing the antiviral immune response is considered taking into account the interacting regulatory influences of the immune and neuroendocrine systems. To describe the innate immunity, the proposed model uses parameters reflecting quantitative measures of the interferon concentration (the inductor of resistance to the infection of target organ cells) and NK-cells (responsible for removing of the infected cells). The simulation of acquired immunity is performed using parameters characterizing the concentration of virus-specific cytotoxic T cells and antibody-forming B lymphocytes. The regulatory mechanisms considered in the model cover the influence of the hypothalamic-pituitary-adrenal axis and the populations of the T-helper cells. The model is developed within the framework of the concept of a multi-level model of the human body, taking into account the interactions between systems and the functional state of the organs included in the review. The model also takes into account the spatial organization of immune and infectious processes in various organs and tissues, for which the delay time of interaction of the components is introduced. The model includes a system of 18 ordinary differential equations with a delayed argument, the parameters of which characterize the rates of various processes that affect the dynamics of infection. The parameters are identified according to published experimental data describing the process of infection of the body with a virus. The dynamics of the immune and neuroendocrine systems under viral infection was calculated, taking into account the disturbance of the synthetic function of the bone marrow. The study provides a qualitative picture of the biological factors that can explain the kinetics of the development of a viral infection.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Assessing the Relation Between Musculoskeletal Disease Prevalence and Physically Demanding Work

Cited by 2 publications

References 0 publications

Assessing index of accumulated cytogenetic disorders in workers employed in metallurgy under exposure to adverse occupaitonal factors

Assessing index of accumulated cytogenetic disorders in workers employed in metallurgy under exposure to adverse occupaitonal factors

Regulation of Organism's Antiviral Immune Response: Mathematical Model, Qualitative Analysis, Results

Contact Info

Product

Resources

About