Assessing the Patient With Arthralgia, Fevers, and Rash

Abstract

Both scenarios imply that the average GRS-BMI should be lower for study participants in earlier birth cohorts. However, we showed (Table 2 in the article and eTable 1 in the Supplement) that genetic risk remained stable across the birth cohorts, despite major changes in BMI. Furthermore, GRS-BMI did not predict mortality for white participants in HRS (P = .45). Additionally, we estimated a model testing whether the birth year by GRS-BMI interaction differed for white respondents above or below age 65 years and found no evidence of such effect modification by age (P = .24).With respect to Mr Liu and Dr Guo, upon reviewing their article, 6 we agree that our results for white respondents substantially overlap with theirs. This type of overlap is always a risk with publicly available data sets such as the HRS, but missing their citation was a mistake on our part. Our manuscript was mostly finished prior to their publication (first full draft completed March 2014). We attempted to update our literature review, but we failed to identify this important publication. We apologize for our error. We consider it an indication of the importance of this research question that it was undertaken by multiple independent research groups, and we are pleased that the findings are consistent.