“…A total of 25 studies investigated the relationship between family size and incurring CHE ( 15 , 16 , 18 – 22 , 24 – 28 , 31 – 43 ). Five studies found that the relationship is not significant ( 16 , 19 , 36 , 38 , 41 ), ten studies found that a large family size is a risk factor ( 18 , 20 , 22 , 24 , 26 , 31 , 32 , 34 , 35 , 40 ) and ten found that a small family size is associated with a higher risk ( 15 , 21 , 25 , 27 , 28 , 33 , 37 , 39 , 42 , 43 ).…”