Transcatheter aortic valve replacement (TAVR) is an established treatment for patients with severe aortic stenosis. Coronary artery disease (CAD) is highly prevalent in approximately more than 65% in patients undergoing TAVR [1], thus, it may require visualization and intervention following valve implantation, particularly as patients age. Due to the supra-annular design of self-expanding valve (SEV) prosthesis, there can be potential difficulties with coronary access [2]. The data regarding this is currently unclear and lacking. We, thus, performed a systematic review and meta-analysis to evaluate the feasibility of selective coronary angiography (CA) and percutaneous coronary intervention (PCI) post-TAVR with SEVs.