A planned interruption of railway infrastructure is a situation where the operation of the track line or the operation of railway transport is limited. If there is also a restriction on the railway infrastructure, it means there will be complications not only for passengers but, above all, for railway undertakings operating freight transport. However, because of the planned railway infrastructure interruption, the quality of services provided not only to passengers but also to freight transport is decreasing. The aim of this paper is to propose effective planned maintenance works based on the analysis and evaluation of the processes performed during the planned railway infrastructure interruption or restriction. The research describes the process of affected railway infrastructure from technical, cost, and safety points of view. A methodological procedure is proposed under the condition of the Czech infrastructure manager. The main method is the calculation of the costs for the railway infrastructure manager and railway operator during the infrastructure interruption. The application part is undertaken using two interrupted lines according to the established alternative timetable in the area of České Budějovice.