Abstract:BackgroundA clinical study comparing the hemodynamic outcomes of transcatheter mitral valve replacement (TMVR) with vs. without Laceration of the Anterior Mitral leaflet to Prevent Outflow Obstruction (LAMPOON) has never been designed nor conducted.AimsTo quantify the hemodynamic impact of LAMPOON in TMVR using patient-specific computational (in silico) models.MaterialsEight subjects from the LAMPOON investigational device exemption trial were included who had acceptable computed tomography (CT) data for analy… Show more
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