Assessing the effect of engineered nanomaterials on the environment and human health

Geary, Sean M.; Morris, Angie S.; Salem, Aliasger K.

doi:10.1016/j.jaci.2016.06.009

Cited by 23 publications

(11 citation statements)

References 9 publications

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“…Exposure to nanofertilizers and nanopesticides, can contribute to health hazards (Sastry 2012). Migration of nanoparticles incorporated in food material to human has also a great and high risks (Berekaa 2015;Sharma et al 2015;Geary et al 2016). In other words, direct exposure of consumers to nanomaterials poses a serious problem to human health.…”

Section: Plant Nanobiotechnology: Needs and Risksmentioning

confidence: 99%

Nanobiotechnology for Plants

Abdalla¹,

Ragab

Fári

et al. 2019

EBSS

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N ANOTECHNOLOGY has been revolutionized penetrating all sectors in our life through the nanoscience as an essential science for a wide range of technologies. Amazing achievements resulted from this nanotechnology including all agricultural fields such as plant nutrition and crop productivity, energy sector, food sector, and plant biotechnology. A conjugation between plant biotechnology and nanotechnology has been produced an important science called plant bio-nanotechnology. Several fields have been invaded through different nanobiotechnology applications in agriculture including (1) the nanotechnology of encapsulated agro-chemicals, (2) the monitoring of different environmental stresses and crop conditions using nanobiosensors, (3) the improvement of crop production and ameliorating plants against diseases and (4) solution several environmental problems. The crop productivity also could be improved using some new agro-chemicals (e.g., nanofertilizers and nanopesticides). These agro-chemicals are very effective in delivering encapsulating nanomaterials and then enhancement the productivity of crops as well as the suppress plant pests and diseases and protecting the environment from pollution. On the other hand, nanoparticles could enter the food chain via different nano-agrochemicals or nano-processed foods. Therefore, many approaches including uptake of nanoparticles by plants, entry and bio-distribution of nanoparticles into the food chain are needed before using of different bionanotechnological tools in agro-production sector. Further new regulations should be created or rebuilt for new approaches in plant bionanotechnology. Therefore, this review will focus on our needs and risks in the plant nanobiotechnology.

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Section: Plant Nanobiotechnology: Needs and Risksmentioning

confidence: 99%

Nanobiotechnology for Plants

Abdalla¹,

Ragab

Fári

et al. 2019

EBSS

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“…Although some toxicological studies on animals and experimental in vitro tests on lung cells are available, exhaustive data on the effects of nanoparticles and nanomaterials on allergies are still lacking. 22 Lastly, environmental chemicals, such as phthalate esters, which are commonly used as plasticizers, or persistent organic pollutants have also been related to asthma and allergy. [23][24][25] Overall, all these effects happen at even low doses of air pollutants, sometimes at much lower levels than air quality standards, and are stronger in subjects who are highly sensitive to allergies.…”

Section: Chemical Air Pollutantsmentioning

confidence: 99%

External exposome and allergic respiratory and skin diseases

Cecchi

D’Amato²,

Annesi‐Maesano

2018

Journal of Allergy and Clinical Immunology

158

141

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Allergies are complex diseases that result from interactions between multiple genetic and environmental factors. However, the increase in allergies observed in the past decades is explained exclusively by environmental changes occurring in the same period. Presently, the exposome, the totality of specific and nonspecific external environmental exposures (external exposome) to which a subject is exposed from preconception onward and their consequences at the organ and cell levels (internal exposome), is being considered to explain the inception, development, and exacerbations of allergic diseases. Among the best-studied environmental factors of the specific external exposome, indoor and outdoor aeroallergens and air pollutants play a key role in the etiopathogenesis of the inflammatory response to allergens and in clinical manifestations of allergic disease. Climate change, urbanization, and loss of biodiversity affect sources, emissions, and concentrations of main aeroallergens and air pollutants and are among the most critical challenges facing the health and quality of life of the still increasing number of allergic patients today and in the coming decades. Thunderstorm-related asthma is a dramatic example of the effects of combined environmental factors and an in vivo model for understanding the mechanisms at work in respiratory allergy. Environment- or lifestyle-driven aberrancies in the gut and skin microbiome composition represent key mediators of allergic diseases. A better knowledge of the effect of the external exposome on allergy development is crucial for urging patients, health professionals, and policymakers to take actions to mitigate the effect of environmental changes and to adapt to them.

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“…Some of the P&Ps to date addressed such timely topics as climate change, asthma in Olympic athletes, effects of engineered nanomaterials, clinical applications for exhaled nitric oxide, effects of tiotropium in asthma treatment, and clinical trial data sharing. [8][9][10][11][12][13]…”

Section: Paradigms and Perspectivesmentioning

confidence: 99%