2024
DOI: 10.3389/fmicb.2024.1376232
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Assessing the causal effects of Eubacterium and Rumphococcus on constipation: a Mendelian randomized study

Xiao Zhang,
Jiang Chen,
Feng He
et al.

Abstract: BackgroundConstipation is affected by a number of risk variables, including cardiovascular disease and growth factors. However, the impacts of gut flora on constipation incidence has not been shown. This work, Single-Variable Mendelian Randomization (SVMR) was utilized to estimate the causal relationship between the Eubacterium genus or Rumphococcus, and constipation.MethodsData for constipation, Eubacterium genus and Rumphococcus were taken from the Integrated Epidemiology Unit (IEU) open GWAS database. Inclu… Show more

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