Assessing the association between age at first sexual intercourse and migraine: a Mendelian randomization study
Guoliang Zhu,
Miao Wang,
Yawen Wang
et al.
Abstract:Background and objectivesAs indicated by observational and genetic variation studies, age at first sexual intercourse (AFS) may be associated with migraine attack, but there is a lack of evidence from real-world studies due to ethical concerns. Therefore, we conducted a Mendelian randomization study to determine the causal relationship between AFS and migraine.MethodsWe extracted instrumental variables from summary data of a genome-wide association study (GWAS) on AFS and migraine and then conducted two-sample… Show more
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