2020
DOI: 10.1038/s41598-020-63964-y
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Assessing TEG6S reliability between devices and across multiple time points: A prospective thromboelastography validation study

Abstract: The TEG6S is a novel haemostasis analyser utilising resonance technology. It offers potentially greater coagulation information and ease of use, however has not been independently validated in a clinical setting. We aimed to determine if the TEG6S is reliable between devices and across time points. We performed a prospective observational study with ethical approval. For interdevice reliability, we performed simultaneous analysis on two TEG6S devices on 25 adult ICU patients. For time point reliability, we per… Show more

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Cited by 14 publications
(13 citation statements)
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“…87 Although TEG®6s continues to measure the same physical properties as earlier systems, it now does so using a resonance method, as changes in clot strength are accompanied by changes in harmonic resonant frequency. 86,88 While ROTEM and TEG tracings appear similar, they are not interchangeable. 84 Parameter names and reference values are different, and clinicians should be familiar with the values for their particular device (Figure 4).…”
Section: Diagnosis and Management Of Coagulopathy Using Standard Lamentioning
confidence: 97%
See 1 more Smart Citation
“…87 Although TEG®6s continues to measure the same physical properties as earlier systems, it now does so using a resonance method, as changes in clot strength are accompanied by changes in harmonic resonant frequency. 86,88 While ROTEM and TEG tracings appear similar, they are not interchangeable. 84 Parameter names and reference values are different, and clinicians should be familiar with the values for their particular device (Figure 4).…”
Section: Diagnosis and Management Of Coagulopathy Using Standard Lamentioning
confidence: 97%
“…84,85 As a clot is formed, movement in both systems is impeded and a tracing is generated. More recently, both systems have been adapted to be more user-friendly and adaptable to true point-of-care testing, with the development of the TEG®6s 86 and ROTEMsigma. 87 Although TEG®6s continues to measure the same physical properties as earlier systems, it now does so using a resonance method, as changes in clot strength are accompanied by changes in harmonic resonant frequency.…”
Section: Diagnosis and Management Of Coagulopathy Using Standard Lamentioning
confidence: 99%
“…Two commercially devices are currently used: the TEG TM (TEG500 and TEG6s) and ROTEM (with a number of different modules including ROTEM platelet). The clinical utility and reliability of thromboelastography have recently been assessed in a prospective validation study [ 54 ]. Moreover, thromboelastographic reference ranges within a population of cirrhotic patients undergoing liver transplantation are now proposed [ 55 ].…”
Section: Laboratory Assessment Of Bleeding Risk In Liver Diseasementioning
confidence: 99%
“… 3) Biomechanical platelet function assays. Biomechanical tests can be broadly grouped into shear flow -based assays [PFA-100/200 ® , PlaCor PRT ® ( Johnson et al, 2012 )], Cone and Plate(let) Analyzer (CPA) [Impact-R ® ( Savion and Varon, 2006 )], and thromboelastography assays [TEG ® ( Korpallova et al, 2018 ), ROTEM ® ( Bolliger et al, 2012b ; Zaky, 2017 ), Sonoclot ® ( Ganter and Hofer, 2008 ), TEG ® 6s ( Lloyd-Donald et al, 2020 ), Quantra ® system ( Ferrante et al, 2016 )]. …”
Section: Commercially Available Platelet Function Tests and Their Clinical Usagementioning
confidence: 99%