Flexibility in a manufacturing fi rm is a strategic choice that advances the fi rm's superior performance. This is especially true in the emerging supply chain, which makes the fi rm's environment particularly turbulent. This paper examines the critical relationships between a manufacturing fi rm's human capital, the fi rm's fl exibility, suppliers' fl exibility, and the fi rm's competitive advantages. Based on questionnaire responses from 201 senior supply chain management professionals in several manufacturing industries, this study establishes direct links between a manufacturing fi rm's human capital and the fi rm's superior fl exibility, and between a manufacturing fi rm's fl exibility and its competitive advantages. In addition, this research fi nds that the fi rm's fl exibility mediates the relationship between the fi rm's human capital and its competitive advantages, as does the connection between the suppliers' fl exibility and the fi rm's competitive advantages.