Assessing statins use in a real-world primary care digital strategy: a cross-sectional analysis of a population-wide digital health approach

Machline-Carrion, M. Julia; Girotto, Alysson Nathan; Nieri, Josué; Pereira, Pedro Marton; Monfardini, Frederico; Forestiero, Francisco; Raupp, Priscila; Roveda, Fabiana; Santo, Karla; Berwanger, Otávio; Santos, Raul D.

doi:10.1016/j.lana.2023.100534

Cited by 4 publications

(8 citation statements)

References 40 publications

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“…Moreover, within the general population characteristics, there was a low percentage of medication use recommended for high-risk individuals, such as those with coronary heart disease or diabetes. Statins, for instance, were used in less than half of these patients, similar to other reports [33,34].…”

Section: Discussionsupporting

confidence: 68%

Clinical Implications of High-Sensitivity Troponin Elevation Levels in Non-ST-Segment Elevation Myocardial Infarction Patients: Beyond Diagnostics

Bravo,

Vizcarra,

Sánchez

et al. 2024

Diagnostics

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Standard troponin has long been pivotal in diagnosing coronary syndrome, especially Non-ST-Segment Elevation Myocardial Infarction (NSTEMI). The recent introduction of high-sensitivity troponin (hs-cTnI) has elevated it to the gold standard. Yet, its nuanced role in predicting angiographic lesions and clinical outcomes, notably in specific populations like obesity, remains underexplored. Aim: To evaluate the association between hs-cTnI magnitude in NSTEMI patients and angiographic findings, progression to acute heart failure, and its performance in obesity. Methods: Retrospective study of 208 NSTEMI patients at a large university center (2020–2023). Hs-cTnI values were assessed for angiographic severity, acute heart failure, and characteristics in the obese population. Data collected and diagnostic performance were evaluated using manufacturer-specified cutoffs. Results: 97.12% of patients had a single culprit vessel. Hs-cTnI elevation correlated with angiographic stenosis severity. Performance for detecting severe coronary disease was low, with no improvement using a higher cutoff. No association was found between hs-cTnI and the culprit vessel location. Hs-cTnI did not predict acute heart failure progression. In the obese population, hs-cTnI levels were higher, but acute heart failure occurred less frequently than in non-obese counterparts. Conclusions: In NSTEMI, hs-cTnI elevation is associated with significant stenosis, but not with location or acute heart failure. Obesity correlates with higher hs-cTnI levels but a reduced risk of acute heart failure during NSTEMI.

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Section: Discussionsupporting

confidence: 68%

Clinical Implications of High-Sensitivity Troponin Elevation Levels in Non-ST-Segment Elevation Myocardial Infarction Patients: Beyond Diagnostics

Bravo,

Vizcarra,

Sánchez

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

“…O uso de estatina foi associado a idade acima de 60 anos, residir na região sul e presença de comorbidades (insuficiência cardíaca, diabetes mellitus ou doença renal crônica). 91 Impacto da Pandemia de COVID-19…”

Section: Qualidade Da Atenção à Saúdeunclassified

“…Idade superior a 60 anos, residir na região sul, diagnósticos prévios de infarto do miocárdio, insuficiência cardíaca, diabetes, dislipidemia e doença renal crônica, além do uso de anti-hipertensivos foram associados ao uso de estatina. 91 …”

Section: Fatores De Risco E Prevençãounclassified

“…•Em análise de registros obtidos da “Estratégia de Saúde da Família “, dados de mundo real sobre o uso de estatinas na prevenção secundária em 2133900 indivíduos de todo território nacional foram reportados. 91 Desses sujeitos, 35103 (idade média 66,2 anos, 49,5% sexo masculino) haviam tido um IAM prévio ou um acidente vascular encefálico. Nessa população o uso de estatinas foi da ordem de 6.7% somente.…”

Section: Conhecimento Tratamento E Controleunclassified

“…Age over 60 years, living in the Southern region, previously diagnose of myocardial infarction, heart failure, diabetes, dyslipidemia, chronic kidney disease, and use of anti-hypertensives were associated with statin use. 91 …”

Section: Risk Factors and Preventionmentioning

confidence: 99%

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