Assessing risk factors for SARS-CoV-2 infection in patients presenting with symptoms in Shanghai, China: a multicentre, observational cohort study

Mao, Baohua; Liu, Yang; Chai, Yan-hua; Jin, Xingming; Lu, Hai‐Wen; Yang, Jai Sing; Gao, Xiwen; Song, Xiaolian; Bao, Hong; Wang, An; Gu, Wenchao; Zhao, Lei; Jie-ping, Pan; Fan, Li; Zhang, Tie-Feng; Qian, Yechang; Du, Chunling; Ding, Wei; Tu, Chunlin; Chu, De-Jie; Li, Chun; Ye, Ling; Luo, Yong; Zheng, Cuixia; Yu, Ronghuan; Qiu, Zhongmin; Cao, Haipeng; Ren, Jiawei; Zhao, Jingya; Wang, Changhui; Lu, Hongzhou; Li, Jun; Hu, Yang; Liang, Shuo; Zhang, Jie; Qu, Jieming; Xu, Jin‐Fu

doi:10.1016/s2589-7500(20)30109-6

Cited by 46 publications

(37 citation statements)

References 27 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…While body temperature remains the main monitoring tool for surveillance of cases, many afebrile patients in our population would have been missed. Our results corroborate findings from a study conducted by Mao et al [11], which assessed 50,000 patients presenting to 25 fever clinics in China, and concluded that fever was not a reliable indicator for COVID-19 screening.…”

Section: Discussionsupporting

confidence: 89%

Risk factors for intensive care unit admission and mortality in hospitalized COVID-19 patients

Ahmed¹,

Arshad²,

Malik

et al. 2020

Acute Crit Care

View full text Add to dashboard Cite

Background This study investigated the clinical features and outcome of hospitalized coronavirus disease 2019 (COVID-19) patients admitted to our quaternary care hospital. Methods In this retrospective cohort study, we included all adult patients with COVID-19 infection admitted to a quaternary care hospital in Pakistan from March 1 to April 15, 2020. The extracted variables included demographics, comorbidities, presenting symptoms, laboratory tests and radiological findings during admission. Outcome measures included in-hospital mortality and length of stay. Results Sixty-six COVID-19 patients were hospitalized during the study period. Sixty-one percent were male and 39% female; mean age was 50.6±19.1 years. Fever and cough were the most common presenting symptoms. Serial chest X-rays showed bilateral pulmonary opacities in 33 (50%) patients. The overall mortality was 14% and mean length of stay was 8.4±8.9 days. Ten patients (15%) required intensive care unit (ICU) care during admission, of which six (9%) were intubated. Age ≥60 years, diabetes, ischemic heart disease, ICU admission, neutrophil to lymphocyte ratio ≥3.3, and international normalized ratio ≥1.2 were associated with increased risk of mortality. Conclusions We found a mortality rate of 14% in hospitalized COVID-19 patients. COVID-19 cases are still increasing exponentially around the world and may overwhelm healthcare systems in many countries soon. Our findings can be used for early identification of patients who may require intensive care and aggressive management in order to improve outcomes.

show abstract

Section: Discussionsupporting

confidence: 89%

Risk factors for intensive care unit admission and mortality in hospitalized COVID-19 patients

Ahmed¹,

Arshad²,

Malik

et al. 2020

Acute Crit Care

View full text Add to dashboard Cite

show abstract

“…This is consistent with previous studies that report leukopenia in COVID-19 patients. 9,13,18 Mao and colleagues showed that leukopenia <4 × 10 9 /L was an independent risk factor for COVID-19 32 but leukopenia defined with such a cut-off point did not reach statistical significance in our analysis. Neutrophilia, on the other hand, has been reported in one-third of COVID-19 patients 11 and non-survivors appeared to have a higher neutrophil count than survivors.…”

Section: Discussioncontrasting

confidence: 66%

Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments: a multicenter case‐control study in Hong Kong

et al. 2020

View full text Add to dashboard Cite

Objectives Little is known about the value of routine clinical assessment in identifying patients with coronavirus disease 2019 (COVID‐19) in the emergency department (ED). We aimed to compare the exposure history, signs and symptoms, laboratory, and radiographic features of ED patients who tested positive and negative for COVID‐19. Methods This was a case‐control study in 7 EDs in Hong Kong from 20 January to 29 February 2020. Thirty‐seven patients with laboratory‐confirmed COVID‐19 were age‐ and sex‐matched to 111 controls. We compared the groups with univariate analysis and calculated the odds ratio (OR) of having COVID‐19 for each characteristic that was significantly different between the groups with adjustment for age and presumed location of acquiring the infection. Results There were no significant differences in patient characteristics and reported symptoms between the groups. A positive contact history within 14 days (adjusted OR 37.61, 95% CI: 10.86–130.19), bilateral chest radiograph shadow (adjusted OR 13.19, 95% CI: 4.66–37.35), having prior medical consultation (adjusted OR 7.43, 95% 2.89–19.09), a lower white blood cell count (adjusted OR 1.30, 95% CI: 1.11–1.51), and a lower platelet count (adjusted OR 1.07, 95% CI: 1.01–1.12) were associated with a higher odds of COVID‐19 separately. A higher neutrophil count was associated with a lower odds of COVID‐19 (adjusted OR 0.77, 95% CI: 0.65–0.91). Conclusion This study highlights a number of clinical features that may be useful in identifying high‐risk patients for early testing and isolation while waiting for the test result. Further studies are warranted to verify the findings.

show abstract

“…In China, during COVID-19 pandemic, the Pain Departments of Shenzen and Wuhan have addressed with telemedicine the problem of outpatients needing pain treatment. Indeed, they have used telemedicine to help patients to administer prescriptions and as guidance for physical at-home exercises for pain relief [ 34 ].…”

Section: New Strategies Of Caring For Chronic Pain Patients During Comentioning

confidence: 99%

Impact of COVID-19 pandemic on chronic pain management: Looking for the best way to deliver care

Puntillo

Giglio²,

Brienza

et al. 2020

Best Practice & Research Clinical Anaesthesiology

106

View full text Add to dashboard Cite

Although pain treatment has been described as a fundamental human right, the Coronavirus disease 2019 (COVID-19) pandemic forced healthcare systems worldwide to redistribute healthcare resources toward intensive care units and other COVID-19 dedicated sites. As most chronic pain services were subsequently deemed non-urgent, all outpatient and elective interventional procedures have been reduced or interrupted during the COVID-19 pandemic in order to reduce the risk of viral spread. The shutdown of pain services jointly to the home lockdown imposed by governments has affected chronic pain management worldwide with additional impact on patients' psychological health. Therefore, the aim of this review is to analyze the impact of COVID-19 pandemic on chronic pain treatment and to address what types of strategies can be implemented or supported in order to overcome imposed limitations in delivery of chronic pain patient care.

show abstract

Assessing risk factors for SARS-CoV-2 infection in patients presenting with symptoms in Shanghai, China: a multicentre, observational cohort study

Cited by 46 publications

References 27 publications

Risk factors for intensive care unit admission and mortality in hospitalized COVID-19 patients

Risk factors for intensive care unit admission and mortality in hospitalized COVID-19 patients

Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments: a multicenter case‐control study in Hong Kong

Impact of COVID-19 pandemic on chronic pain management: Looking for the best way to deliver care

Contact Info

Product

Resources

About